Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

Yong Jun Choi, Yae Jean Kim, Dongeun Yong, Jung Hyun Byun, Taek Soo Kim, Yun Sil Chang, Min Ji Choi, Seung Ah Byeon, Eun Jeong Won, Soo Hyun Kim, Myung Geun Shin, Jong Hee Shin

Research output: Contribution to journalLetter

6 Citations (Scopus)

Abstract

We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

Original languageEnglish
Pages (from-to)1768-1770
Number of pages3
JournalEmerging infectious diseases
Volume24
Issue number9
DOIs
Publication statusPublished - 2018 Sep

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Republic of Korea
Fluconazole
Candida
Mutation
Microsatellite Repeats
Genes

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Choi, Yong Jun ; Kim, Yae Jean ; Yong, Dongeun ; Byun, Jung Hyun ; Kim, Taek Soo ; Chang, Yun Sil ; Choi, Min Ji ; Byeon, Seung Ah ; Won, Eun Jeong ; Kim, Soo Hyun ; Shin, Myung Geun ; Shin, Jong Hee. / Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea. In: Emerging infectious diseases. 2018 ; Vol. 24, No. 9. pp. 1768-1770.
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abstract = "We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.",
author = "Choi, {Yong Jun} and Kim, {Yae Jean} and Dongeun Yong and Byun, {Jung Hyun} and Kim, {Taek Soo} and Chang, {Yun Sil} and Choi, {Min Ji} and Byeon, {Seung Ah} and Won, {Eun Jeong} and Kim, {Soo Hyun} and Shin, {Myung Geun} and Shin, {Jong Hee}",
year = "2018",
month = "9",
doi = "10.3201/eid2409.180625",
language = "English",
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pages = "1768--1770",
journal = "Emerging Infectious Diseases",
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Choi, YJ, Kim, YJ, Yong, D, Byun, JH, Kim, TS, Chang, YS, Choi, MJ, Byeon, SA, Won, EJ, Kim, SH, Shin, MG & Shin, JH 2018, 'Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea', Emerging infectious diseases, vol. 24, no. 9, pp. 1768-1770. https://doi.org/10.3201/eid2409.180625

Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea. / Choi, Yong Jun; Kim, Yae Jean; Yong, Dongeun; Byun, Jung Hyun; Kim, Taek Soo; Chang, Yun Sil; Choi, Min Ji; Byeon, Seung Ah; Won, Eun Jeong; Kim, Soo Hyun; Shin, Myung Geun; Shin, Jong Hee.

In: Emerging infectious diseases, Vol. 24, No. 9, 09.2018, p. 1768-1770.

Research output: Contribution to journalLetter

TY - JOUR

T1 - Fluconazole-resistant candida parapsilosis bloodstream isolates with Y132F mutation in ERG11 gene, South Korea

AU - Choi, Yong Jun

AU - Kim, Yae Jean

AU - Yong, Dongeun

AU - Byun, Jung Hyun

AU - Kim, Taek Soo

AU - Chang, Yun Sil

AU - Choi, Min Ji

AU - Byeon, Seung Ah

AU - Won, Eun Jeong

AU - Kim, Soo Hyun

AU - Shin, Myung Geun

AU - Shin, Jong Hee

PY - 2018/9

Y1 - 2018/9

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AB - We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.

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