Fluorographene and Graphane as an Excellent Platform for Enzyme Biocatalysis

Soňa Hermanová, Daniel Bouša, Vlastimil Mazánek, David Sedmidubský, Jan Plutnar, Martin Pumera, Zdeněk Sofer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The application of enzymes is a crucial issue for current biotechnological application in pharmaceutical, as well as food and cosmetic industry. Effective platforms for enzyme immobilization are necessary for their industrial use in various biosynthesis procedures. Such platforms must provide high yield of immobilization and retain high activity at various conditions for their large-scale applications. Graphene derivatives such as hydrogenated graphene (graphane) and fluorographene can be applied for enzyme immobilization with close to 100 % yield that can result to activities of the composites significantly exceeding activity of free enzymes. The hydrophobic properties of graphene stoichiometric derivatives allowed for excellent non-covalent bonding of enzymes and their use in various organic solvents. The immobilized enzymes retain their high activities even at elevated temperatures. These findings show excellent application potential of enzyme biocatalysts immobilized on graphene stoichiometric derivatives.

Original languageEnglish
Pages (from-to)16833-16839
Number of pages7
JournalChemistry - A European Journal
Volume24
Issue number63
DOIs
Publication statusPublished - 2018 Nov 13

Fingerprint

Graphite
Enzymes
Graphene
Enzyme immobilization
Derivatives
Immobilized Enzymes
Biocatalysts
Cosmetics
Biosynthesis
Drug products
Organic solvents
Biocatalysis
Composite materials
Pharmaceutical Preparations
Industry
Temperature

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

Cite this

Hermanová, S., Bouša, D., Mazánek, V., Sedmidubský, D., Plutnar, J., Pumera, M., & Sofer, Z. (2018). Fluorographene and Graphane as an Excellent Platform for Enzyme Biocatalysis. Chemistry - A European Journal, 24(63), 16833-16839. https://doi.org/10.1002/chem.201803397
Hermanová, Soňa ; Bouša, Daniel ; Mazánek, Vlastimil ; Sedmidubský, David ; Plutnar, Jan ; Pumera, Martin ; Sofer, Zdeněk. / Fluorographene and Graphane as an Excellent Platform for Enzyme Biocatalysis. In: Chemistry - A European Journal. 2018 ; Vol. 24, No. 63. pp. 16833-16839.
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Hermanová, S, Bouša, D, Mazánek, V, Sedmidubský, D, Plutnar, J, Pumera, M & Sofer, Z 2018, 'Fluorographene and Graphane as an Excellent Platform for Enzyme Biocatalysis', Chemistry - A European Journal, vol. 24, no. 63, pp. 16833-16839. https://doi.org/10.1002/chem.201803397

Fluorographene and Graphane as an Excellent Platform for Enzyme Biocatalysis. / Hermanová, Soňa; Bouša, Daniel; Mazánek, Vlastimil; Sedmidubský, David; Plutnar, Jan; Pumera, Martin; Sofer, Zdeněk.

In: Chemistry - A European Journal, Vol. 24, No. 63, 13.11.2018, p. 16833-16839.

Research output: Contribution to journalArticle

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Hermanová S, Bouša D, Mazánek V, Sedmidubský D, Plutnar J, Pumera M et al. Fluorographene and Graphane as an Excellent Platform for Enzyme Biocatalysis. Chemistry - A European Journal. 2018 Nov 13;24(63):16833-16839. https://doi.org/10.1002/chem.201803397