Focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions: Imaging findings and clinical relevance

Jai Kyung You, Eun Kyung Kim, Jin Young Kwak, Min Jung Kim, Ki Keun Oh, Byeong Woo Park, Woo Ik Yang

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

Objective. The purpose of this study was to evaluate the frequency of focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions, to characterize imaging features, and to evaluate their clinical relevance. Methods. In a retrospective review of 724 lesions that underwent sonographically guided core biopsy of nonpalpable breast lesions, 62 cases had a diagnosis of focal fibrosis. Two radiologists analyzed the sonographic and mammographic findings according to the Breast Imaging Reporting and Data System. The results were compared with histologic findings at surgery or imaging findings during surveillance. Results. The incidence of focal fibrosis was 8.6% (62/724). Sonographic films were available in 56 cases, so 56 cases were reviewed for their sonographic findings. Among the mammograms reviewed, 64.7% (33/51) had negative findings. Among the sonograms reviewed, the most common features were oval shape (32/56, 57.1%), parallel orientation (36/56, 64.3%), microlobulated margin (24/56, 42.9%), abrupt interface (50/56, 89.3%), isoechoic pattern (42/56, 75.0%), and a lack of posterior acoustic features (45/56, 80.4%). The Breast Imaging Reporting and Data System final assessment was category 3 in 27 (48.2%) and category 4 in 29 (51.8%). Most of the category 4 lesions were category 4A (26/29, 89.7%). Surgical excision (n = 7) and follow-up for at least 1 year (n = 49) showed no malignancy. Conclusions. Focal fibrosis was found in 8.6% by a sonographically guided core biopsy of nonpalpable breast lesions. Most of the lesions were categorized as probably benign (category 3) or having a low suggestion of malignancy (category 4A). Focal fibrosis diagnosed at core biopsy can be managed with a 6-month follow-up protocol.

Original languageEnglish
Pages (from-to)1377-1384
Number of pages8
JournalJournal of Ultrasound in Medicine
Volume24
Issue number10
DOIs
Publication statusPublished - 2005 Oct

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Breast
Fibrosis
Biopsy
Information Systems
Acoustics
Neoplasms
Incidence

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

@article{25038e9d09b44cb28bc0c471b06a250d,
title = "Focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions: Imaging findings and clinical relevance",
abstract = "Objective. The purpose of this study was to evaluate the frequency of focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions, to characterize imaging features, and to evaluate their clinical relevance. Methods. In a retrospective review of 724 lesions that underwent sonographically guided core biopsy of nonpalpable breast lesions, 62 cases had a diagnosis of focal fibrosis. Two radiologists analyzed the sonographic and mammographic findings according to the Breast Imaging Reporting and Data System. The results were compared with histologic findings at surgery or imaging findings during surveillance. Results. The incidence of focal fibrosis was 8.6{\%} (62/724). Sonographic films were available in 56 cases, so 56 cases were reviewed for their sonographic findings. Among the mammograms reviewed, 64.7{\%} (33/51) had negative findings. Among the sonograms reviewed, the most common features were oval shape (32/56, 57.1{\%}), parallel orientation (36/56, 64.3{\%}), microlobulated margin (24/56, 42.9{\%}), abrupt interface (50/56, 89.3{\%}), isoechoic pattern (42/56, 75.0{\%}), and a lack of posterior acoustic features (45/56, 80.4{\%}). The Breast Imaging Reporting and Data System final assessment was category 3 in 27 (48.2{\%}) and category 4 in 29 (51.8{\%}). Most of the category 4 lesions were category 4A (26/29, 89.7{\%}). Surgical excision (n = 7) and follow-up for at least 1 year (n = 49) showed no malignancy. Conclusions. Focal fibrosis was found in 8.6{\%} by a sonographically guided core biopsy of nonpalpable breast lesions. Most of the lesions were categorized as probably benign (category 3) or having a low suggestion of malignancy (category 4A). Focal fibrosis diagnosed at core biopsy can be managed with a 6-month follow-up protocol.",
author = "You, {Jai Kyung} and Kim, {Eun Kyung} and Kwak, {Jin Young} and Kim, {Min Jung} and Oh, {Ki Keun} and Park, {Byeong Woo} and Yang, {Woo Ik}",
year = "2005",
month = "10",
doi = "10.7863/jum.2005.24.10.1377",
language = "English",
volume = "24",
pages = "1377--1384",
journal = "Journal of Ultrasound in Medicine",
issn = "0278-4297",
publisher = "American Institute of Ultrasound in Medicine",
number = "10",

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TY - JOUR

T1 - Focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions

T2 - Imaging findings and clinical relevance

AU - You, Jai Kyung

AU - Kim, Eun Kyung

AU - Kwak, Jin Young

AU - Kim, Min Jung

AU - Oh, Ki Keun

AU - Park, Byeong Woo

AU - Yang, Woo Ik

PY - 2005/10

Y1 - 2005/10

N2 - Objective. The purpose of this study was to evaluate the frequency of focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions, to characterize imaging features, and to evaluate their clinical relevance. Methods. In a retrospective review of 724 lesions that underwent sonographically guided core biopsy of nonpalpable breast lesions, 62 cases had a diagnosis of focal fibrosis. Two radiologists analyzed the sonographic and mammographic findings according to the Breast Imaging Reporting and Data System. The results were compared with histologic findings at surgery or imaging findings during surveillance. Results. The incidence of focal fibrosis was 8.6% (62/724). Sonographic films were available in 56 cases, so 56 cases were reviewed for their sonographic findings. Among the mammograms reviewed, 64.7% (33/51) had negative findings. Among the sonograms reviewed, the most common features were oval shape (32/56, 57.1%), parallel orientation (36/56, 64.3%), microlobulated margin (24/56, 42.9%), abrupt interface (50/56, 89.3%), isoechoic pattern (42/56, 75.0%), and a lack of posterior acoustic features (45/56, 80.4%). The Breast Imaging Reporting and Data System final assessment was category 3 in 27 (48.2%) and category 4 in 29 (51.8%). Most of the category 4 lesions were category 4A (26/29, 89.7%). Surgical excision (n = 7) and follow-up for at least 1 year (n = 49) showed no malignancy. Conclusions. Focal fibrosis was found in 8.6% by a sonographically guided core biopsy of nonpalpable breast lesions. Most of the lesions were categorized as probably benign (category 3) or having a low suggestion of malignancy (category 4A). Focal fibrosis diagnosed at core biopsy can be managed with a 6-month follow-up protocol.

AB - Objective. The purpose of this study was to evaluate the frequency of focal fibrosis of the breast diagnosed by a sonographically guided core biopsy of nonpalpable lesions, to characterize imaging features, and to evaluate their clinical relevance. Methods. In a retrospective review of 724 lesions that underwent sonographically guided core biopsy of nonpalpable breast lesions, 62 cases had a diagnosis of focal fibrosis. Two radiologists analyzed the sonographic and mammographic findings according to the Breast Imaging Reporting and Data System. The results were compared with histologic findings at surgery or imaging findings during surveillance. Results. The incidence of focal fibrosis was 8.6% (62/724). Sonographic films were available in 56 cases, so 56 cases were reviewed for their sonographic findings. Among the mammograms reviewed, 64.7% (33/51) had negative findings. Among the sonograms reviewed, the most common features were oval shape (32/56, 57.1%), parallel orientation (36/56, 64.3%), microlobulated margin (24/56, 42.9%), abrupt interface (50/56, 89.3%), isoechoic pattern (42/56, 75.0%), and a lack of posterior acoustic features (45/56, 80.4%). The Breast Imaging Reporting and Data System final assessment was category 3 in 27 (48.2%) and category 4 in 29 (51.8%). Most of the category 4 lesions were category 4A (26/29, 89.7%). Surgical excision (n = 7) and follow-up for at least 1 year (n = 49) showed no malignancy. Conclusions. Focal fibrosis was found in 8.6% by a sonographically guided core biopsy of nonpalpable breast lesions. Most of the lesions were categorized as probably benign (category 3) or having a low suggestion of malignancy (category 4A). Focal fibrosis diagnosed at core biopsy can be managed with a 6-month follow-up protocol.

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