Follicular dendritic cell sarcoma presenting as a submucosal tumor of the stomach

J. H. Han, S. H. Kim, S. H. Noh, Y. C. Lee, H. G. Kim, W. I. Yang

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Abstract

Follicular dendritic cell (FDC) sarcomas, especially those of extranodal origin, are extremely rare, and this entity could easily be missed without a high index of suspicion. We report a case of FDC sarcoma presenting as a submucosal tumor of the stomach in a 45-year-old man. The mass was a spindle and epithelioid mesenchymal tumor with many individually scattered and perivascular aggregates of lymphocytes. Immunohistochemical and ultrastructural studies confirmed the diagnosis. Although more than 50 cases of this tumor have been documented in the English literature, to our knowledge the presentation of FDC sarcoma as a submucosal tumor of the stomach has never been recorded. This case highlights the occurrence of FDC sarcoma as a submucosal tumor of the gastrointestinal tract. We believe that FDC sarcoma should be included in the differential diagnosis of spindle or epithelioid cell tumors of the gastrointestinal hollow viscus to prevent this still underrecognized tumor from being overlooked.

Original languageEnglish
Pages (from-to)1693-1696
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume124
Issue number11
Publication statusPublished - 2000 Nov 30

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All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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