Hyperthermia treatment system has a long history in medical. It has been regarded as an effective treatment for tumor cells as the efficacy and safety of it is proved. The effect of treatment can be enhanced when chemotherapy and radiation oncology are performed with heated tumor cell by hyperthermia treatment system . The hyperthermia system using a microwave for the treatment of superficial tumor is in general adopt the frequencies at 433 MHz and 915 MHz to satisfy the temperature evenness occurred in targeted medium and the penetrating depth where superficial tumor existed . The various heat distributions in targeted medium can be induced by varying the operating frequency. The hyperthermia system which has various frequencies for treatment is suitable and effective to patients who have tumor cells that has various shapes in various positions. In this paper, a frequency reconfigurable antenna operating at 433 MHz and 915 MHz as a radiator of superficial hyperthermia system is proposed. The system operating at both frequencies can improve the curative effect more than the system with a single frequency. Using the superficial hyperthermia system which makes different heat distributions can be a treatment for different symptoms of the patients by applies the proposed antenna using two different frequencies.