Functional diversification of MYB23 and GL1 genes in trichome morphogenesis and initiation

Victor Kirik, Myeong Min Lee, Katja Wester, Ullrich Herrmann, Zhengui Zheng, David Oppenheimer, John Schiefelbein, Martin Hulskamp

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127 Citations (Scopus)

Abstract

The functional diversification of duplicated genes is one of the driving forces in evolution. To understand the molecular mechanisms of gene diversification, we studied the functional relationship of the two Arabidopsis paralogous MYB-related genes GL1 and MYB23. We show that MYB23 controls trichome branching and trichome initiation at leaf edges. The latter is controlled redundantly together with GL1. We show that the two proteins are functionally equivalent during trichome initiation but not during trichome branching. RT-PCR and reporter construct analysis revealed spatial, temporal and genetic differences in transcriptional regulation of the GL1 and MYB23 genes. Presented data indicate that the diversification of GL1 and MYB23 gene functions occurred at the level of cis-regulatory sequences with respect to trichome initiation, and that, in parallel, the diversification with respect to regulation of trichome branching also involved changes in respective proteins.

Original languageEnglish
Pages (from-to)1477-1485
Number of pages9
JournalDevelopment
Volume132
Issue number7
DOIs
Publication statusPublished - 2005 Apr

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Developmental Biology

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    Kirik, V., Lee, M. M., Wester, K., Herrmann, U., Zheng, Z., Oppenheimer, D., Schiefelbein, J., & Hulskamp, M. (2005). Functional diversification of MYB23 and GL1 genes in trichome morphogenesis and initiation. Development, 132(7), 1477-1485. https://doi.org/10.1242/dev.01708