A putative gene for a transcriptional regulator (ophR) was detected near each copy of the duplicated phthalate-degrading operon of Rhodococcus sp. DK17. Sequence analysis and molecular modeling indicate that OphR belongs to the IclR family of transcriptional regulators and possesses the N-terminal DNA-binding and C-terminal effector-binding domains. DNA-binding assays demonstrate that OphR regulates the phthalate operon by binding to the ophA1-ophR intergenic region.
Bibliographical noteFunding Information:
This work was financially supported by a grant from the Ministry of Oceans and Fisheries, Korea to the Korea Polar Research Institute (Project PM13030).
© 2015, Association of Microbiologists of India.
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