Functional Identification of OphR, an IclR Family Transcriptional Regulator Involved in the Regulation of the Phthalate Catabolic Operon in Rhodococcus sp. Strain DK17

Ki Young Choi, Beom Sik Kang, Myung Hee Nam, Woo Jun Sul, Eungbin Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A putative gene for a transcriptional regulator (ophR) was detected near each copy of the duplicated phthalate-degrading operon of Rhodococcus sp. DK17. Sequence analysis and molecular modeling indicate that OphR belongs to the IclR family of transcriptional regulators and possesses the N-terminal DNA-binding and C-terminal effector-binding domains. DNA-binding assays demonstrate that OphR regulates the phthalate operon by binding to the ophA1-ophR intergenic region.

Original languageEnglish
Pages (from-to)313-318
Number of pages6
JournalIndian Journal of Microbiology
Volume55
Issue number3
DOIs
Publication statusPublished - 2015 Sep 6

All Science Journal Classification (ASJC) codes

  • Microbiology

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