Functionalized inclined-GaN based nanoneedles

Kwon Ho Kim, Kyuseung Lee, Hyeonaug Hong, Dasom Yang, WonHyoung Ryu, Okhyun Nam, Yeu Chun Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Techniques for the delivery foreign materials into living cells as well as for sensing have undeniable worth in cell biology research. A major barrier for intracellular delivery is to cross the cell membrane with little or no damage. Among the various intracellular delivery methods, one-dimensional nanoneedles are one of the promising methods for insertion with minimal invasiveness to a cell. Most of the previous studies have been conducted using vertical nanoneedle. Here, we synthesized new inclined nanoneedles and demonstrated a novel platform using inclined-gallium nitride nanoneedles (iGaN NNs) to facilitate efficient intracellular delivery. In our system, foreign molecules were successfully delivered into cytoplasm of a cell through the penetration of the cell membrane by the iGaN NNs.

Original languageEnglish
Pages (from-to)184-191
Number of pages8
JournalJournal of Industrial and Engineering Chemistry
Volume59
DOIs
Publication statusPublished - 2018 Mar 25

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Nanoneedles
Cell membranes
Cytology
Gallium nitride
Cells
Molecules

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)

Cite this

Kim, Kwon Ho ; Lee, Kyuseung ; Hong, Hyeonaug ; Yang, Dasom ; Ryu, WonHyoung ; Nam, Okhyun ; Kim, Yeu Chun. / Functionalized inclined-GaN based nanoneedles. In: Journal of Industrial and Engineering Chemistry. 2018 ; Vol. 59. pp. 184-191.
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Functionalized inclined-GaN based nanoneedles. / Kim, Kwon Ho; Lee, Kyuseung; Hong, Hyeonaug; Yang, Dasom; Ryu, WonHyoung; Nam, Okhyun; Kim, Yeu Chun.

In: Journal of Industrial and Engineering Chemistry, Vol. 59, 25.03.2018, p. 184-191.

Research output: Contribution to journalArticle

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