Funneling of gibberellin signaling by the GRAS transcription regulator SCARECROW-LIKE 3 in the Arabidopsis root

Jung Ok Heo, Kwang Suk Chang, In A. Kim, Mi Hyun Lee, Shin Ae Lee, Sang Kee Song, Myeong Min Lee, Jun Lim

Research output: Contribution to journalArticle

109 Citations (Scopus)

Abstract

During plant development, because no cell movement takes place, control of the timing and extent of cell division and coordination of the direction and extent of cell expansion are particularly important for growth and development. The plant hormone gibberellins (GAs) play key roles in the control of these developmental processes. However, little is known about the molecular components that integrate the generic GA signaling into a specific cell/tissue to coordinate cell division and cell expansion. Here we report that SCARECROW-LIKE 3 (SCL3), a GRAS protein, acts as a positive regulator to integrate and maintain a functional GA pathway by attenuating the DELLA repressors in the root endodermis. The tissue-specific maintenance of GA signaling in the root endodermis plays distinct roles along the longitudinal root axis. While in the elongation/differentiation zone (EDZ), the endodermis-confined GA pathway by SCL3 controls primarily coordination of root cell elongation; in the meristem zone (MZ) SCL3 in conjunction with the SHORT-ROOT/SCARECROW (SHR/SCR) pathway controls GA-modulated ground tissue maturation. Our findings highlight the regulatory network of the GRAS transcription regulators (SCL3, DELLAs, and SHR/SCR) in the root endodermis, shedding light on how GA homeostasis is achieved and how the maintenance of GA signaling controls developmental processes in roots.

Original languageEnglish
Pages (from-to)2166-2171
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume108
Issue number5
DOIs
Publication statusPublished - 2011 Feb 1

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Gibberellins
Arabidopsis
Cell Division
Maintenance
Plant Growth Regulators
Plant Development
Meristem
Growth and Development
Cell Movement
Homeostasis
Proteins

All Science Journal Classification (ASJC) codes

  • General

Cite this

Heo, Jung Ok ; Chang, Kwang Suk ; Kim, In A. ; Lee, Mi Hyun ; Lee, Shin Ae ; Song, Sang Kee ; Lee, Myeong Min ; Lim, Jun. / Funneling of gibberellin signaling by the GRAS transcription regulator SCARECROW-LIKE 3 in the Arabidopsis root. In: Proceedings of the National Academy of Sciences of the United States of America. 2011 ; Vol. 108, No. 5. pp. 2166-2171.
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Funneling of gibberellin signaling by the GRAS transcription regulator SCARECROW-LIKE 3 in the Arabidopsis root. / Heo, Jung Ok; Chang, Kwang Suk; Kim, In A.; Lee, Mi Hyun; Lee, Shin Ae; Song, Sang Kee; Lee, Myeong Min; Lim, Jun.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 5, 01.02.2011, p. 2166-2171.

Research output: Contribution to journalArticle

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