Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance

Kyungwon Lee, Ki Hyung Park, Seok Hoon Jeong, Hwan Sub Lim, Jong Hee Shin, Dongeun Yong, Gyoung Yim Ha, Yunsop Chong, Jae Seok Kim, Sunjoo Kim, Namhee Ryoo, Mun Yeun Kim, Chulhun L. Chang, Mi Na Kim, Wee Gyo Lee, Myungshin Kim, Chea Hoon Lee, Jeong Ho Kim, Joseph Jeong, Ji Hyun ChoYoung Uh, Ki Sook Hong, Bo Moon Shin, Hye Soo Lee, Sook Jin Jang, Ae Ja Park, Young Joo Cha, Young Jin Choi, Sung Ha Kang, Chang Hyun Rhim, Myung Hee Lee, Wonkeun Song, Tae Yeal Choi, Eui Chong Kim, Jung Oak Kang, Yeon Joon Park, Seong Geun Hong, Ah Kim Young, Hee Joo Lee, Jongwook Lee, Young Joon Lee, Miae Lee, Hee Bong Shin, Young Ree Kim, Seung Ok Lee, Sung Hee Lee

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Monitoring temporal trends of antimicrobial resistance can provide useful information for the empirical selection of antimicrobial agents to treat infected patients and for the control of nosocomial infections. In this study, we analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory. The following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%). expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40%). Moreover, gradual increases, in vancomycin-resistant Enterococcus faecium (20%), cefoxitin-resistant E. coli (10%) and K. pneumoniae (23%), and imipenem-resistant P. aeruginosa (20%) and Acinetobacter spp. (13%): were also observed. The resistance rates of Acinetobacter spp. to most antimicrobial agents at hospitals and at the commercial laboratory were similar. Among the Acinetobacter spp. isolated at a tertiary-care hospital, 46.2% were multidrug-resistant to 9-12 of 13 antimicrobial agents, and 18.3% were panresistant. The exclusion of duplicate isolates at a tertiary-care hospital significantly lowered the proportion of oxacillin-resistant S. aureus, vancomycin-resistant E. faecium, and fluoroquinolone-resistant E coli.

Original languageEnglish
Pages (from-to)43-54
Number of pages12
JournalYonsei medical journal
Volume47
Issue number1
DOIs
Publication statusPublished - 2006 Feb 6

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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    Lee, K., Park, K. H., Jeong, S. H., Lim, H. S., Shin, J. H., Yong, D., Ha, G. Y., Chong, Y., Kim, J. S., Kim, S., Ryoo, N., Kim, M. Y., Chang, C. L., Kim, M. N., Lee, W. G., Kim, M., Lee, C. H., Kim, J. H., Jeong, J., ... Lee, S. H. (2006). Further increase of vancomycin-resistant Enterococcus faecium, amikacin- and fluoroquinolone-resistant Klebsiella pneumoniae, and imipenem-resistant Acinetobacter spp. in Korea: 2003 KONSAR surveillance. Yonsei medical journal, 47(1), 43-54. https://doi.org/10.3349/ymj.2006.47.1.43