Gadolinium-chlorin is potentially a new tumor specific MRI contrast agent

Jong Ki Kim; Dong Myung Kim; Min Suk Kang; Hae Kyung Kim; Jeong Sook Kim; Eun Kyung Yu; Jin Hyun Jeong

doi:10.1007/BF02969390

Gadolinium-chlorin is potentially a new tumor specific MRI contrast agent

Jong Ki Kim, Dong Myung Kim, Min Suk Kang, Hae Kyung Kim, Jeong Sook Kim, Eun Kyung Yu, Jin Hyun Jeong

Department of Pharmacy

Research output: Contribution to journal › Article

6 Citations (Scopus)

Abstract

In this study, a newly-synthesized metalloporphyrin, Gd-chlorin (PB Chlorin), was investigated by using a simple tissue phantom to test its efficacy as an MRI contrast agent. This study demonstrated the potential activity of Gd-chlorin as not only a MRI contrast agent, but also as a PDT photosensitizer by using a simple tissue phantom and conducting a very brief MRI experiment.

Original language	English
Pages (from-to)	188-190
Number of pages	3
Journal	Archives of pharmacal research
Volume	29
Issue number	3
DOIs	https://doi.org/10.1007/BF02969390
Publication status	Published - 2006 Mar 31

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All Science Journal Classification (ASJC) codes

Molecular Medicine
Drug Discovery
Organic Chemistry

Cite this

Kim, J. K., Kim, D. M., Kang, M. S., Kim, H. K., Kim, J. S., Yu, E. K., & Jeong, J. H. (2006). Gadolinium-chlorin is potentially a new tumor specific MRI contrast agent. Archives of pharmacal research, 29(3), 188-190. https://doi.org/10.1007/BF02969390

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abstract = "In this study, a newly-synthesized metalloporphyrin, Gd-chlorin (PB Chlorin), was investigated by using a simple tissue phantom to test its efficacy as an MRI contrast agent. This study demonstrated the potential activity of Gd-chlorin as not only a MRI contrast agent, but also as a PDT photosensitizer by using a simple tissue phantom and conducting a very brief MRI experiment.",

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10.1007/BF02969390