Gene × Environment interaction between DRD2 and criminal father is associated with five antisocial phenotypes

Matt Delisi, Kevin M. Beaver, Michael George Vaughn, John Paul Wright

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

A range of Gene × Environment interactions is associated with antisocial phenotypes, and the evidence is clear that the etiology of antisocial behavior is strongly heritable and that environmental liabilities are important. However, the precise ways that genetic and environmental pathogens interact to predict antisocial behavior are underspecified. The present study shows that the interaction between a polymorphism in a dopamine receptor gene (DRD2) and a criminal father predicts five antisocial phenotypes among African American females (n = 232) in the National Longitudinal Study of Adolescent Health. Genetic risk (as measured by the A1 allele) and a criminal father interacted to predict serious and violent delinquency at Wave 1, serious and violent delinquency at Wave 2, and number of police contacts. The current investigation represents the first study to show Gene × Environment interactions in the prediction of antisocial phenotypes using criminal justice system status as an environmental pathogen.

Original languageEnglish
Pages (from-to)1187-1197
Number of pages11
JournalCriminal Justice and Behavior
Volume36
Issue number11
DOIs
Publication statusPublished - 2009 Nov 1

Fingerprint

Gene-Environment Interaction
Fathers
father
delinquency
Phenotype
interaction
National Longitudinal Study of Adolescent Health
Criminal Law
Dopamine Receptors
Police
etiology
African Americans
liability
longitudinal study
police
justice
Alleles
contact
adolescent
health

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Psychology(all)
  • Law

Cite this

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Gene × Environment interaction between DRD2 and criminal father is associated with five antisocial phenotypes. / Delisi, Matt; Beaver, Kevin M.; Vaughn, Michael George; Wright, John Paul.

In: Criminal Justice and Behavior, Vol. 36, No. 11, 01.11.2009, p. 1187-1197.

Research output: Contribution to journalArticle

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