Genetic mutations in linezolid-resistant Mycobacterium avium complex and Mycobacterium abscessus clinical isolates

Su Young Kim, Byung Woo Jhun, Seong Mi Moon, Kyeongman Jeon, O. Jung Kwon, Hee Jae Huh, Nam Yong Lee, Sung Jae Shin, Charles L. Daley, Won Jung Koh

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

There are no studies evaluating the mechanisms driving linezolid resistance in nontuberculous mycobacteria. The novel mutations G2599A and A2137T in the 23S rRNA gene and mutations A439G and G443A in the rplD gene associated with linezolid resistance were identified in linezolid-resistant M. avium complex isolates.

Original languageEnglish
Pages (from-to)38-40
Number of pages3
JournalDiagnostic Microbiology and Infectious Disease
Volume94
Issue number1
DOIs
Publication statusPublished - 2019 May

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Science, Information and Communications Technologies (NRF-2018R1A2A1A05018309 to W-J. K.), and by the Basic Science Research Program through the NRF funded by the Ministry of Education (NRF-2016R1A6A3A11930364 to S.-Y.K.).

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Science, Information and Communications Technologies (NRF-2018R1A2A1A05018309 to W-J. K.), and by the Basic Science Research Program through the NRF funded by the Ministry of Education ( NRF-2016R1A6A3A11930364 to S.-Y.K.).

Publisher Copyright:
© 2018 Elsevier Inc.

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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