Gold @ silica core-shell nanoparticle for enhanced surface plasmon resonance detection of DNA hybridization in combination with gold nanowire gratings

Seyoung Moon, Youngjin Oh, Donghyun Kim, Hosub Lee, Hyun Chang Kim, Kangtaek Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Metallic nanoparticles have drawn much interest due to their distinct plasmonic characteristics especially in imaging and sensing applications. Surface plasmon resonance (SPR) based biosensors have evolved in many ways, among which sensitivity enhancement towards molecular sensing capability came up with strategies to overcome the hard limit of the intrinsic sensitivity of gold thin film. Recently adoption of signal contrast materials has proven successful in biochemical sensing applications. This study employs gold-SiO2 core-shell nanoparticles (CSNPs) as a strong SPR signal contrast agents. To reveal the underlying physics for the contrast mechanism, the particle characteristics were analytically evaluated in terms of light interaction coefficients. We experimentally demonstrate the effect of the CSNPs by applying them to acquire enhanced signal in DNA hybridization sensing scheme. We also applied gold nanowire grating structure on conventional gold thin film to further amplify the intrinsic sensitivity, where localized surface plasmon and locally amplified evanescent fields take parts. The results suggest that CSNPs and the grating structure cooperatively enhance the sensitivity and the role of nanowire gratings was analyzed with numerical methods to allow optimum sensitivity enhancement in terms of fill factor variations. The effects of field localization, amplification and enlarged signature of CSNPs are also discussed.

Original languageEnglish
Title of host publicationBiosensing and Nanomedicine IV
Volume8099
DOIs
Publication statusPublished - 2011 Oct 19
EventBiosensing and Nanomedicine IV - San Diego, CA, United States
Duration: 2011 Aug 212011 Aug 23

Other

OtherBiosensing and Nanomedicine IV
CountryUnited States
CitySan Diego, CA
Period11/8/2111/8/23

Fingerprint

Surface Plasmon
Nanowires
Surface plasmon resonance
Silica
surface plasmon resonance
Gold
Silicon Dioxide
Gratings
Nanoparticles
Shell
DNA
nanowires
deoxyribonucleic acid
gratings
gold
silicon dioxide
Sensing
nanoparticles
sensitivity
Contrast Media

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

@inproceedings{261fafb9f45b42f58ac08b1e88eb5370,
title = "Gold @ silica core-shell nanoparticle for enhanced surface plasmon resonance detection of DNA hybridization in combination with gold nanowire gratings",
abstract = "Metallic nanoparticles have drawn much interest due to their distinct plasmonic characteristics especially in imaging and sensing applications. Surface plasmon resonance (SPR) based biosensors have evolved in many ways, among which sensitivity enhancement towards molecular sensing capability came up with strategies to overcome the hard limit of the intrinsic sensitivity of gold thin film. Recently adoption of signal contrast materials has proven successful in biochemical sensing applications. This study employs gold-SiO2 core-shell nanoparticles (CSNPs) as a strong SPR signal contrast agents. To reveal the underlying physics for the contrast mechanism, the particle characteristics were analytically evaluated in terms of light interaction coefficients. We experimentally demonstrate the effect of the CSNPs by applying them to acquire enhanced signal in DNA hybridization sensing scheme. We also applied gold nanowire grating structure on conventional gold thin film to further amplify the intrinsic sensitivity, where localized surface plasmon and locally amplified evanescent fields take parts. The results suggest that CSNPs and the grating structure cooperatively enhance the sensitivity and the role of nanowire gratings was analyzed with numerical methods to allow optimum sensitivity enhancement in terms of fill factor variations. The effects of field localization, amplification and enlarged signature of CSNPs are also discussed.",
author = "Seyoung Moon and Youngjin Oh and Donghyun Kim and Hosub Lee and Kim, {Hyun Chang} and Kangtaek Lee",
year = "2011",
month = "10",
day = "19",
doi = "10.1117/12.894214",
language = "English",
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Moon, S, Oh, Y, Kim, D, Lee, H, Kim, HC & Lee, K 2011, Gold @ silica core-shell nanoparticle for enhanced surface plasmon resonance detection of DNA hybridization in combination with gold nanowire gratings. in Biosensing and Nanomedicine IV. vol. 8099, 809914, Biosensing and Nanomedicine IV, San Diego, CA, United States, 11/8/21. https://doi.org/10.1117/12.894214

Gold @ silica core-shell nanoparticle for enhanced surface plasmon resonance detection of DNA hybridization in combination with gold nanowire gratings. / Moon, Seyoung; Oh, Youngjin; Kim, Donghyun; Lee, Hosub; Kim, Hyun Chang; Lee, Kangtaek.

Biosensing and Nanomedicine IV. Vol. 8099 2011. 809914.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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AU - Oh, Youngjin

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AU - Lee, Hosub

AU - Kim, Hyun Chang

AU - Lee, Kangtaek

PY - 2011/10/19

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N2 - Metallic nanoparticles have drawn much interest due to their distinct plasmonic characteristics especially in imaging and sensing applications. Surface plasmon resonance (SPR) based biosensors have evolved in many ways, among which sensitivity enhancement towards molecular sensing capability came up with strategies to overcome the hard limit of the intrinsic sensitivity of gold thin film. Recently adoption of signal contrast materials has proven successful in biochemical sensing applications. This study employs gold-SiO2 core-shell nanoparticles (CSNPs) as a strong SPR signal contrast agents. To reveal the underlying physics for the contrast mechanism, the particle characteristics were analytically evaluated in terms of light interaction coefficients. We experimentally demonstrate the effect of the CSNPs by applying them to acquire enhanced signal in DNA hybridization sensing scheme. We also applied gold nanowire grating structure on conventional gold thin film to further amplify the intrinsic sensitivity, where localized surface plasmon and locally amplified evanescent fields take parts. The results suggest that CSNPs and the grating structure cooperatively enhance the sensitivity and the role of nanowire gratings was analyzed with numerical methods to allow optimum sensitivity enhancement in terms of fill factor variations. The effects of field localization, amplification and enlarged signature of CSNPs are also discussed.

AB - Metallic nanoparticles have drawn much interest due to their distinct plasmonic characteristics especially in imaging and sensing applications. Surface plasmon resonance (SPR) based biosensors have evolved in many ways, among which sensitivity enhancement towards molecular sensing capability came up with strategies to overcome the hard limit of the intrinsic sensitivity of gold thin film. Recently adoption of signal contrast materials has proven successful in biochemical sensing applications. This study employs gold-SiO2 core-shell nanoparticles (CSNPs) as a strong SPR signal contrast agents. To reveal the underlying physics for the contrast mechanism, the particle characteristics were analytically evaluated in terms of light interaction coefficients. We experimentally demonstrate the effect of the CSNPs by applying them to acquire enhanced signal in DNA hybridization sensing scheme. We also applied gold nanowire grating structure on conventional gold thin film to further amplify the intrinsic sensitivity, where localized surface plasmon and locally amplified evanescent fields take parts. The results suggest that CSNPs and the grating structure cooperatively enhance the sensitivity and the role of nanowire gratings was analyzed with numerical methods to allow optimum sensitivity enhancement in terms of fill factor variations. The effects of field localization, amplification and enlarged signature of CSNPs are also discussed.

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