TY - JOUR
T1 - Graft survival after video-assisted minilaparotomy living-donor nephrectomy or conventional open nephrectomy
T2 - Do left and right allografts differ?
AU - Yoon, Young Eun
AU - Han, Woong Kyu
AU - Choi, Kyung Hwa
AU - Yang, Seung Choul
AU - Kim, Yu Seun
AU - Kang, Dae Ryong
AU - Huh, Kyu Ha
AU - Kim, Myoung Soo
AU - Kim, Soon Il
AU - Joo, Dong Jin
N1 - Funding Information:
Funding Support: This work was supported by a research grant from a newly appointed professor, Yonsei University College of Medicine ( 8-2012-0076 ).
Publisher Copyright:
© 2014 Elsevier Inc. All rights reserved.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Objective To examine the effect of the side of the allograft (left vs right) on early graft failure and long-term graft survival rates after conventional open living-donor nephrectomy (OLDN) or video-assisted minilaparotomy living-donor nephrectomy (VLDN). Materials and Methods We evaluated 2704 living-donor transplantations using OLDN or VLDN between 1991 and 2011 at a single institution. For analysis, the entire period was divided into "era 1" (1991-1997), when OLDN was prevalent; "era 2" (1998-2004), when both OLDN and VLDN were conducted; and "era 3" (2005-2011), when VLDN became prevalent. Results There were 822, 650, and 685 transplantations analyzed in eras 1, 2, and 3, respectively. There were no differences in causes of early graft failure between left and right allografts in any era. The right allograft survival rate in eras 1 and 2 was slightly lower than the left allograft survival rate. In era 2, during which both OLDN and VLDN were conducted, Kaplan-Meier analysis showed lower right allograft survival rate for OLDN. However, the long-term survival rates of the left and right VLDN grafts did not differ. Conclusion Right OLDN allografts demonstrated worse long-term survival rate than left OLDN allografts, but the right and left VLDN allografts had similar long-term survival rate. VLDN appears to be an appropriate treatment option when right donor nephrectomy is desired.
AB - Objective To examine the effect of the side of the allograft (left vs right) on early graft failure and long-term graft survival rates after conventional open living-donor nephrectomy (OLDN) or video-assisted minilaparotomy living-donor nephrectomy (VLDN). Materials and Methods We evaluated 2704 living-donor transplantations using OLDN or VLDN between 1991 and 2011 at a single institution. For analysis, the entire period was divided into "era 1" (1991-1997), when OLDN was prevalent; "era 2" (1998-2004), when both OLDN and VLDN were conducted; and "era 3" (2005-2011), when VLDN became prevalent. Results There were 822, 650, and 685 transplantations analyzed in eras 1, 2, and 3, respectively. There were no differences in causes of early graft failure between left and right allografts in any era. The right allograft survival rate in eras 1 and 2 was slightly lower than the left allograft survival rate. In era 2, during which both OLDN and VLDN were conducted, Kaplan-Meier analysis showed lower right allograft survival rate for OLDN. However, the long-term survival rates of the left and right VLDN grafts did not differ. Conclusion Right OLDN allografts demonstrated worse long-term survival rate than left OLDN allografts, but the right and left VLDN allografts had similar long-term survival rate. VLDN appears to be an appropriate treatment option when right donor nephrectomy is desired.
UR - http://www.scopus.com/inward/record.url?scp=84921978693&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84921978693&partnerID=8YFLogxK
U2 - 10.1016/j.urology.2014.06.028
DO - 10.1016/j.urology.2014.06.028
M3 - Article
C2 - 25156512
AN - SCOPUS:84921978693
SN - 0090-4295
VL - 84
SP - 832
EP - 837
JO - Urology
JF - Urology
IS - 4
ER -