Radiomische Merkmale im B-Bild und in der Scherwellen-Elastografie bei benignen und malignen Raumforderungen der Brust

Translated title of the contribution: Grayscale ultrasound radiomic features and shear-wave elastography radiomic features in benign and malignant breast masses

Ji Hyun Youk, Jin Young Kwak, Eunjung Lee, Eun Ju Son, Jeong Ah Kim

Research output: Contribution to journalArticle

Abstract

Purpose To identify and compare diagnostic performance of radiomic features between grayscale ultrasound (US) and shear-wave elastography (SWE) in breast masses. Materials and Methods We retrospectively collected 328 pathologically confirmed breast masses in 296 women who underwent grayscale US and SWE before biopsy or surgery. A representative SWE image of the mass displayed with a grayscale image in split-screen mode was selected. An ROI was delineated around the mass boundary on the grayscale image and copied and pasted to the SWE image by a dedicated breast radiologist for lesion segmentation. A total of 730 candidate radiomic features including first-order statistics and textural and wavelet features were extracted from each image. LASSO regression was used for data dimension reduction and feature selection. Univariate and multivariate logistic regression was performed to identify independent radiomic features, differentiating between benign and malignant masses with calculation of the AUC. Results Of 328 breast masses, 205 (62.5 %) were benign and 123 (37.5 %) were malignant. Following radiomic feature selection, 22 features from grayscale and 6 features from SWE remained. On univariate analysis, all 6 SWE radiomic features (P < 0.0001) and 21 of 22 grayscale radiomic features (P < 0.03) were significantly different between benign and malignant masses. After multivariate analysis, three grayscale radiomic features and two SWE radiomic features were independently associated with malignant breast masses. The AUC was 0.929 for grayscale US and 0.992 for SWE (P < 0.001). Conclusion US radiomic features may have the potential to improve diagnostic performance for breast masses, but further investigation of independent and larger datasets is needed.

Translated title of the contributionGrayscale ultrasound radiomic features and shear-wave elastography radiomic features in benign and malignant breast masses
Original languageGerman
Pages (from-to)390-396
Number of pages7
JournalUltraschall in der Medizin
Volume41
Issue number4
DOIs
Publication statusPublished - 2020 Aug 1

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Grayscale ultrasound radiomic features and shear-wave elastography radiomic features in benign and malignant breast masses'. Together they form a unique fingerprint.

  • Cite this