Five hundred and thirty-two nanometers laser light evokes neuron-specific electrical responses in identified neurons of Helix ganglia. Such responses are intensity-dependent over the range 25-1500 mW, readily reversible and repeatable. Detailed experiments on the C1 neuron, which is inhibited by 532 nm light, showed that inhibition results from a selective increase in transmembrane Cl- ion conductance. Experiments with calcium-sensitive microelectrodes suggest that the response does not result from an increase in [Ca2+]i. The change in Cl- ion conductance probably occurs in the extensive plasmalemma infoldings of the proximal axon.
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We are grateful to the EPSRC for financial support.
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