Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG

Jin Hyun Chung, Hye Ryun Lim, Tek Hyung Lee, Mi Hee Lee, Yeon I. Woo, Hyun Sook Baek, Seung Jin Lee, Jeong Koo Kim, Jong Chul Park

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalKey Engineering Materials
Volume342-343
DOIs
Publication statusPublished - 2007

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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    Chung, J. H., Lim, H. R., Lee, T. H., Lee, M. H., Woo, Y. I., Baek, H. S., Lee, S. J., Kim, J. K., & Park, J. C. (2007). Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG. Key Engineering Materials, 342-343, 93-96. https://doi.org/10.4028/0-87849-436-7.93