Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG

Jin Hyun Chung, Hye Ryun Lim, Tek Hyung Lee, Mi Hee Lee, Yeon I. Woo, Hyun Sook Baek, Seung Jin Lee, Jeong Koo Kim, Jongchul Park

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.

Original languageEnglish
Pages (from-to)93-96
Number of pages4
JournalKey Engineering Materials
Volume342-343
Publication statusPublished - 2007 Apr 16

Fingerprint

Endothelial cells
Scaffolds
Muscle
Cells
glycolic acid
Blood vessels
Acetone
Acids
epigallocatechin gallate
polylactic acid-polyglycolic acid copolymer

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Chemical Engineering (miscellaneous)

Cite this

Chung, J. H., Lim, H. R., Lee, T. H., Lee, M. H., Woo, Y. I., Baek, H. S., ... Park, J. (2007). Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG. Key Engineering Materials, 342-343, 93-96.
Chung, Jin Hyun ; Lim, Hye Ryun ; Lee, Tek Hyung ; Lee, Mi Hee ; Woo, Yeon I. ; Baek, Hyun Sook ; Lee, Seung Jin ; Kim, Jeong Koo ; Park, Jongchul. / Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG. In: Key Engineering Materials. 2007 ; Vol. 342-343. pp. 93-96.
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Chung, JH, Lim, HR, Lee, TH, Lee, MH, Woo, YI, Baek, HS, Lee, SJ, Kim, JK & Park, J 2007, 'Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG', Key Engineering Materials, vol. 342-343, pp. 93-96.

Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG. / Chung, Jin Hyun; Lim, Hye Ryun; Lee, Tek Hyung; Lee, Mi Hee; Woo, Yeon I.; Baek, Hyun Sook; Lee, Seung Jin; Kim, Jeong Koo; Park, Jongchul.

In: Key Engineering Materials, Vol. 342-343, 16.04.2007, p. 93-96.

Research output: Contribution to journalArticle

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T1 - Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG

AU - Chung, Jin Hyun

AU - Lim, Hye Ryun

AU - Lee, Tek Hyung

AU - Lee, Mi Hee

AU - Woo, Yeon I.

AU - Baek, Hyun Sook

AU - Lee, Seung Jin

AU - Kim, Jeong Koo

AU - Park, Jongchul

PY - 2007/4/16

Y1 - 2007/4/16

N2 - Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.

AB - Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested.

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Chung JH, Lim HR, Lee TH, Lee MH, Woo YI, Baek HS et al. Growth of smooth muscle cell and endothelial cell on PLGA film containing EGCG. Key Engineering Materials. 2007 Apr 16;342-343:93-96.