Haemodynamic effects of a milrinone infusion without a bolus in patients undergoing off-pump coronary artery bypass graft surgery

Y. L. Kwak, Y. J. Oh, H. K. Shinn, K. J. Yoo, S. H. Kim, Y. W. Hong

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The haemodynamic effects of a continuous infusion of milrinone without an initial bolus dose were evaluated in patients undergoing off-pump coronary artery bypass graft surgery. After internal mammary artery harvest, milrinone 0.5 υg.min-1.kg-1 (29 patients) or a normal saline infusion (33 patients) was started and continued until all graft anastomoses were completed. Haemodynamic variables were recorded before application of the tissue stabiliser, at 1, 3, 5 and 10 min after the application of the stabiliser, and after its removal. The administration of a milrinone infusion was associated with a smaller decrease in cardiac output and mixed venous oxygen saturation during all the coronary artery anastomoses, with no severe complications and a decreased dose of norepinephrine infused to maintain systemic arterial pressure.

Original languageEnglish
Pages (from-to)324-331
Number of pages8
Issue number4
Publication statusPublished - 2004 Apr 1


All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

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