Haemodynamic effects of a milrinone infusion without a bolus in patients undergoing off-pump coronary artery bypass graft surgery

Y. L. Kwak, Y. J. Oh, H. K. Shinn, K. J. Yoo, S. H. Kim, Y. W. Hong

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The haemodynamic effects of a continuous infusion of milrinone without an initial bolus dose were evaluated in patients undergoing off-pump coronary artery bypass graft surgery. After internal mammary artery harvest, milrinone 0.5 υg.min-1.kg-1 (29 patients) or a normal saline infusion (33 patients) was started and continued until all graft anastomoses were completed. Haemodynamic variables were recorded before application of the tissue stabiliser, at 1, 3, 5 and 10 min after the application of the stabiliser, and after its removal. The administration of a milrinone infusion was associated with a smaller decrease in cardiac output and mixed venous oxygen saturation during all the coronary artery anastomoses, with no severe complications and a decreased dose of norepinephrine infused to maintain systemic arterial pressure.

Original languageEnglish
Pages (from-to)324-331
Number of pages8
JournalAnaesthesia
Volume59
Issue number4
DOIs
Publication statusPublished - 2004 Apr 1

Fingerprint

Milrinone
Off-Pump Coronary Artery Bypass
Coronary Artery Bypass
Hemodynamics
Transplants
Mammary Arteries
Cardiac Output
Coronary Vessels
Norepinephrine
Arterial Pressure
Oxygen

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

Kwak, Y. L. ; Oh, Y. J. ; Shinn, H. K. ; Yoo, K. J. ; Kim, S. H. ; Hong, Y. W. / Haemodynamic effects of a milrinone infusion without a bolus in patients undergoing off-pump coronary artery bypass graft surgery. In: Anaesthesia. 2004 ; Vol. 59, No. 4. pp. 324-331.
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Haemodynamic effects of a milrinone infusion without a bolus in patients undergoing off-pump coronary artery bypass graft surgery. / Kwak, Y. L.; Oh, Y. J.; Shinn, H. K.; Yoo, K. J.; Kim, S. H.; Hong, Y. W.

In: Anaesthesia, Vol. 59, No. 4, 01.04.2004, p. 324-331.

Research output: Contribution to journalArticle

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