Haemodynamic evaluation by Doppler ultrasonography in patients with portal hypertension: A review

Research output: Contribution to journalReview article

42 Citations (Scopus)

Abstract

Doppler ultrasonography (US) has an advantage of being non-invasive; therefore, several attempts have been made to investigate the haemodynamic alterations in cirrhosis and the response to medical treatment of portal hypertension. Doppler indices, which have been commonly used for the evaluation of portal hypertension, include the measurement of portal and splenic venous blood velocity and flows, and the resistive and pulsatility index at hepatic, splenic, renal, superior mesenteric artery. Although many positive evidences have been suggested, its clinical usefulness in portal hypertension remains unsettled because of being plagued by lack of reproducibility and accuracy characterized by intra- and interobserver variation. However, recently, Doppler's usefulness in assessment of severity of portal hypertension in terms of reproducibility, technical ease and accuracy and response to drugs that reduce the portal pressure has been proposed. In addition, because most of the patients with cirrhosis and portal hypertension have intrahepatic shunts, they show a decrease in intrahepatic circulatory time (IHCT). Doppler US using microbubble contrast agents allows measurement of IHCT. Therefore, application of contrast-enhanced Doppler US can be prospective for the assessment of the severity of portal hypertension. Several reports have demonstrated that colour Doppler endoscopic US enable haemodynamic study to assess the portal hypertension and has a role of guidance to measure the imaging-based variceal pressure. We have reviewed briefly the clinical usefulness of Doppler US in assessing the severity of portal hypertension and its response to treatment.

Original languageEnglish
Pages (from-to)1403-1413
Number of pages11
JournalLiver International
Volume30
Issue number10
DOIs
Publication statusPublished - 2010 Nov 1

Fingerprint

Doppler Ultrasonography
Portal Hypertension
Hemodynamics
Fibrosis
Portal Pressure
Microbubbles
Endosonography
Superior Mesenteric Artery
Observer Variation
Blood Flow Velocity
Contrast Media
Color
Kidney
Pressure
Liver
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hepatology

Cite this

@article{1b4c5a9400e54cafaf408a6884a9ec08,
title = "Haemodynamic evaluation by Doppler ultrasonography in patients with portal hypertension: A review",
abstract = "Doppler ultrasonography (US) has an advantage of being non-invasive; therefore, several attempts have been made to investigate the haemodynamic alterations in cirrhosis and the response to medical treatment of portal hypertension. Doppler indices, which have been commonly used for the evaluation of portal hypertension, include the measurement of portal and splenic venous blood velocity and flows, and the resistive and pulsatility index at hepatic, splenic, renal, superior mesenteric artery. Although many positive evidences have been suggested, its clinical usefulness in portal hypertension remains unsettled because of being plagued by lack of reproducibility and accuracy characterized by intra- and interobserver variation. However, recently, Doppler's usefulness in assessment of severity of portal hypertension in terms of reproducibility, technical ease and accuracy and response to drugs that reduce the portal pressure has been proposed. In addition, because most of the patients with cirrhosis and portal hypertension have intrahepatic shunts, they show a decrease in intrahepatic circulatory time (IHCT). Doppler US using microbubble contrast agents allows measurement of IHCT. Therefore, application of contrast-enhanced Doppler US can be prospective for the assessment of the severity of portal hypertension. Several reports have demonstrated that colour Doppler endoscopic US enable haemodynamic study to assess the portal hypertension and has a role of guidance to measure the imaging-based variceal pressure. We have reviewed briefly the clinical usefulness of Doppler US in assessing the severity of portal hypertension and its response to treatment.",
author = "Soonkoo Baik",
year = "2010",
month = "11",
day = "1",
doi = "10.1111/j.1478-3231.2010.02326.x",
language = "English",
volume = "30",
pages = "1403--1413",
journal = "Liver International",
issn = "1478-3223",
publisher = "Wiley-Blackwell",
number = "10",

}

Haemodynamic evaluation by Doppler ultrasonography in patients with portal hypertension : A review. / Baik, Soonkoo.

In: Liver International, Vol. 30, No. 10, 01.11.2010, p. 1403-1413.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Haemodynamic evaluation by Doppler ultrasonography in patients with portal hypertension

T2 - A review

AU - Baik, Soonkoo

PY - 2010/11/1

Y1 - 2010/11/1

N2 - Doppler ultrasonography (US) has an advantage of being non-invasive; therefore, several attempts have been made to investigate the haemodynamic alterations in cirrhosis and the response to medical treatment of portal hypertension. Doppler indices, which have been commonly used for the evaluation of portal hypertension, include the measurement of portal and splenic venous blood velocity and flows, and the resistive and pulsatility index at hepatic, splenic, renal, superior mesenteric artery. Although many positive evidences have been suggested, its clinical usefulness in portal hypertension remains unsettled because of being plagued by lack of reproducibility and accuracy characterized by intra- and interobserver variation. However, recently, Doppler's usefulness in assessment of severity of portal hypertension in terms of reproducibility, technical ease and accuracy and response to drugs that reduce the portal pressure has been proposed. In addition, because most of the patients with cirrhosis and portal hypertension have intrahepatic shunts, they show a decrease in intrahepatic circulatory time (IHCT). Doppler US using microbubble contrast agents allows measurement of IHCT. Therefore, application of contrast-enhanced Doppler US can be prospective for the assessment of the severity of portal hypertension. Several reports have demonstrated that colour Doppler endoscopic US enable haemodynamic study to assess the portal hypertension and has a role of guidance to measure the imaging-based variceal pressure. We have reviewed briefly the clinical usefulness of Doppler US in assessing the severity of portal hypertension and its response to treatment.

AB - Doppler ultrasonography (US) has an advantage of being non-invasive; therefore, several attempts have been made to investigate the haemodynamic alterations in cirrhosis and the response to medical treatment of portal hypertension. Doppler indices, which have been commonly used for the evaluation of portal hypertension, include the measurement of portal and splenic venous blood velocity and flows, and the resistive and pulsatility index at hepatic, splenic, renal, superior mesenteric artery. Although many positive evidences have been suggested, its clinical usefulness in portal hypertension remains unsettled because of being plagued by lack of reproducibility and accuracy characterized by intra- and interobserver variation. However, recently, Doppler's usefulness in assessment of severity of portal hypertension in terms of reproducibility, technical ease and accuracy and response to drugs that reduce the portal pressure has been proposed. In addition, because most of the patients with cirrhosis and portal hypertension have intrahepatic shunts, they show a decrease in intrahepatic circulatory time (IHCT). Doppler US using microbubble contrast agents allows measurement of IHCT. Therefore, application of contrast-enhanced Doppler US can be prospective for the assessment of the severity of portal hypertension. Several reports have demonstrated that colour Doppler endoscopic US enable haemodynamic study to assess the portal hypertension and has a role of guidance to measure the imaging-based variceal pressure. We have reviewed briefly the clinical usefulness of Doppler US in assessing the severity of portal hypertension and its response to treatment.

UR - http://www.scopus.com/inward/record.url?scp=79951589886&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79951589886&partnerID=8YFLogxK

U2 - 10.1111/j.1478-3231.2010.02326.x

DO - 10.1111/j.1478-3231.2010.02326.x

M3 - Review article

C2 - 20731772

AN - SCOPUS:79951589886

VL - 30

SP - 1403

EP - 1413

JO - Liver International

JF - Liver International

SN - 1478-3223

IS - 10

ER -