Hair regeneration using adipose-derived stem cells

Su Eon Jin, Jong Hyuk Sung

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Adipose-derived stem cells (ASCs) have been used in tissue repair and regeneration. Recently, it was reported that ASC transplantation promotes hair growth in animal experiments, and a conditioned medium of ASCs (ASC-CM) induced the proliferation of hair-compositing cells in vitro. However, ASCs and their conditioned medium have shown limited effectiveness in clinical settings. ASC preconditioning is one strategy that can be used to enhance the efficacy of ASCs and ASC-CM. Therefore, we highlighted the functional role of ASCs in hair cycle progression and also the advantages and disadvantages of their application in hair regeneration. In addition, we introduced novel ASC preconditioning methods to enhance hair regeneration using ASC stimulators, such as vitamin C, platelet-derived growth factor, hypoxia, and ultraviolet B.

Original languageEnglish
Pages (from-to)249-256
Number of pages8
JournalHistology and Histopathology
Volume31
Issue number3
DOIs
Publication statusPublished - 2016 Mar 1

Fingerprint

Regeneration
Stem Cells
Conditioned Culture Medium
Platelet-Derived Growth Factor
Stem Cell Transplantation
Ascorbic Acid
Growth

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

Cite this

@article{7bea918597504a88aa41eef0f855eb77,
title = "Hair regeneration using adipose-derived stem cells",
abstract = "Adipose-derived stem cells (ASCs) have been used in tissue repair and regeneration. Recently, it was reported that ASC transplantation promotes hair growth in animal experiments, and a conditioned medium of ASCs (ASC-CM) induced the proliferation of hair-compositing cells in vitro. However, ASCs and their conditioned medium have shown limited effectiveness in clinical settings. ASC preconditioning is one strategy that can be used to enhance the efficacy of ASCs and ASC-CM. Therefore, we highlighted the functional role of ASCs in hair cycle progression and also the advantages and disadvantages of their application in hair regeneration. In addition, we introduced novel ASC preconditioning methods to enhance hair regeneration using ASC stimulators, such as vitamin C, platelet-derived growth factor, hypoxia, and ultraviolet B.",
author = "Jin, {Su Eon} and Sung, {Jong Hyuk}",
year = "2016",
month = "3",
day = "1",
doi = "10.14670/HH-11-686",
language = "English",
volume = "31",
pages = "249--256",
journal = "Histology and Histopathology",
issn = "0213-3911",
publisher = "Histology and Histopathology",
number = "3",

}

Hair regeneration using adipose-derived stem cells. / Jin, Su Eon; Sung, Jong Hyuk.

In: Histology and Histopathology, Vol. 31, No. 3, 01.03.2016, p. 249-256.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Hair regeneration using adipose-derived stem cells

AU - Jin, Su Eon

AU - Sung, Jong Hyuk

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Adipose-derived stem cells (ASCs) have been used in tissue repair and regeneration. Recently, it was reported that ASC transplantation promotes hair growth in animal experiments, and a conditioned medium of ASCs (ASC-CM) induced the proliferation of hair-compositing cells in vitro. However, ASCs and their conditioned medium have shown limited effectiveness in clinical settings. ASC preconditioning is one strategy that can be used to enhance the efficacy of ASCs and ASC-CM. Therefore, we highlighted the functional role of ASCs in hair cycle progression and also the advantages and disadvantages of their application in hair regeneration. In addition, we introduced novel ASC preconditioning methods to enhance hair regeneration using ASC stimulators, such as vitamin C, platelet-derived growth factor, hypoxia, and ultraviolet B.

AB - Adipose-derived stem cells (ASCs) have been used in tissue repair and regeneration. Recently, it was reported that ASC transplantation promotes hair growth in animal experiments, and a conditioned medium of ASCs (ASC-CM) induced the proliferation of hair-compositing cells in vitro. However, ASCs and their conditioned medium have shown limited effectiveness in clinical settings. ASC preconditioning is one strategy that can be used to enhance the efficacy of ASCs and ASC-CM. Therefore, we highlighted the functional role of ASCs in hair cycle progression and also the advantages and disadvantages of their application in hair regeneration. In addition, we introduced novel ASC preconditioning methods to enhance hair regeneration using ASC stimulators, such as vitamin C, platelet-derived growth factor, hypoxia, and ultraviolet B.

UR - http://www.scopus.com/inward/record.url?scp=84957605418&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957605418&partnerID=8YFLogxK

U2 - 10.14670/HH-11-686

DO - 10.14670/HH-11-686

M3 - Review article

C2 - 26536569

AN - SCOPUS:84957605418

VL - 31

SP - 249

EP - 256

JO - Histology and Histopathology

JF - Histology and Histopathology

SN - 0213-3911

IS - 3

ER -