TY - JOUR
T1 - Handgrip Strength as a Predictor of All-Cause Mortality in Patients With Chronic Kidney Disease Undergoing Dialysis
T2 - A Meta-Analysis of Prospective Cohort Studies
AU - Hwang, Seo Hyeon
AU - Lee, Dong Hoon
AU - Min, Jihee
AU - Jeon, Justin Y.
PY - 2019/11
Y1 - 2019/11
N2 - The aim of this study was to conduct a meta-analysis of the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis. We evaluated eligible studies by searching PubMed and EMBASE databases up to December 2, 2018. A total of 9 prospective cohort studies were included in this meta-analysis. When we compared patients with low HGS to those with high HGS, the summary risk ratio of all-cause mortality was 1.88 (95% confidence interval 1.51-2.33; P < .001). In addition, the summary risk ratio of all-cause mortality associated with a 1-kg unit increase in HGS was 0.95 (95% confidence interval 0.93-0.97; P < .001). This quantitative synthesis showed that low HGS was associated with increased risk of all-cause mortality in patients with chronic kidney disease undergoing dialysis. Our study suggests that HGS may be a simple and useful predictor of prognosis in this patient population.
AB - The aim of this study was to conduct a meta-analysis of the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis. We evaluated eligible studies by searching PubMed and EMBASE databases up to December 2, 2018. A total of 9 prospective cohort studies were included in this meta-analysis. When we compared patients with low HGS to those with high HGS, the summary risk ratio of all-cause mortality was 1.88 (95% confidence interval 1.51-2.33; P < .001). In addition, the summary risk ratio of all-cause mortality associated with a 1-kg unit increase in HGS was 0.95 (95% confidence interval 0.93-0.97; P < .001). This quantitative synthesis showed that low HGS was associated with increased risk of all-cause mortality in patients with chronic kidney disease undergoing dialysis. Our study suggests that HGS may be a simple and useful predictor of prognosis in this patient population.
UR - http://www.scopus.com/inward/record.url?scp=85062151122&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85062151122&partnerID=8YFLogxK
U2 - 10.1053/j.jrn.2019.01.002
DO - 10.1053/j.jrn.2019.01.002
M3 - Review article
C2 - 30827839
AN - SCOPUS:85062151122
VL - 29
SP - 471
EP - 479
JO - Journal of Renal Nutrition
JF - Journal of Renal Nutrition
SN - 1051-2276
IS - 6
ER -