Abstract
The aim of this study was to conduct a meta-analysis of the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis. We evaluated eligible studies by searching PubMed and EMBASE databases up to December 2, 2018. A total of 9 prospective cohort studies were included in this meta-analysis. When we compared patients with low HGS to those with high HGS, the summary risk ratio of all-cause mortality was 1.88 (95% confidence interval 1.51-2.33; P <.001). In addition, the summary risk ratio of all-cause mortality associated with a 1-kg unit increase in HGS was 0.95 (95% confidence interval 0.93-0.97; P <.001). This quantitative synthesis showed that low HGS was associated with increased risk of all-cause mortality in patients with chronic kidney disease undergoing dialysis. Our study suggests that HGS may be a simple and useful predictor of prognosis in this patient population.
| Original language | English |
|---|---|
| Journal | Journal of Renal Nutrition |
| DOIs | |
| Publication status | Published - 2019 Jan 1 |
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All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Nephrology
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Handgrip Strength as a Predictor of All-Cause Mortality in Patients With Chronic Kidney Disease Undergoing Dialysis : A Meta-Analysis of Prospective Cohort Studies. / Hwang, Seo Hyeon; Lee, Dong Hoon; Min, Jihee; Jeon, Justin Y.
In: Journal of Renal Nutrition, 01.01.2019.Research output: Contribution to journal › Review article
TY - JOUR
T1 - Handgrip Strength as a Predictor of All-Cause Mortality in Patients With Chronic Kidney Disease Undergoing Dialysis
T2 - A Meta-Analysis of Prospective Cohort Studies
AU - Hwang, Seo Hyeon
AU - Lee, Dong Hoon
AU - Min, Jihee
AU - Jeon, Justin Y.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The aim of this study was to conduct a meta-analysis of the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis. We evaluated eligible studies by searching PubMed and EMBASE databases up to December 2, 2018. A total of 9 prospective cohort studies were included in this meta-analysis. When we compared patients with low HGS to those with high HGS, the summary risk ratio of all-cause mortality was 1.88 (95% confidence interval 1.51-2.33; P <.001). In addition, the summary risk ratio of all-cause mortality associated with a 1-kg unit increase in HGS was 0.95 (95% confidence interval 0.93-0.97; P <.001). This quantitative synthesis showed that low HGS was associated with increased risk of all-cause mortality in patients with chronic kidney disease undergoing dialysis. Our study suggests that HGS may be a simple and useful predictor of prognosis in this patient population.
AB - The aim of this study was to conduct a meta-analysis of the association between handgrip strength (HGS) and all-cause mortality in patients with chronic kidney disease undergoing dialysis. We evaluated eligible studies by searching PubMed and EMBASE databases up to December 2, 2018. A total of 9 prospective cohort studies were included in this meta-analysis. When we compared patients with low HGS to those with high HGS, the summary risk ratio of all-cause mortality was 1.88 (95% confidence interval 1.51-2.33; P <.001). In addition, the summary risk ratio of all-cause mortality associated with a 1-kg unit increase in HGS was 0.95 (95% confidence interval 0.93-0.97; P <.001). This quantitative synthesis showed that low HGS was associated with increased risk of all-cause mortality in patients with chronic kidney disease undergoing dialysis. Our study suggests that HGS may be a simple and useful predictor of prognosis in this patient population.
UR - http://www.scopus.com/inward/record.url?scp=85062151122&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85062151122&partnerID=8YFLogxK
U2 - 10.1053/j.jrn.2019.01.002
DO - 10.1053/j.jrn.2019.01.002
M3 - Review article
JO - Journal of Renal Nutrition
JF - Journal of Renal Nutrition
SN - 1051-2276
ER -