Health literacy and mortality in patients with heart failure: A systematic review and meta-analysis

Xibei B. Liu, Yousef Ayatollahi, Takashi Yamashita, Mohamed Jaradat, Jay J. Shen, Sun Jung Kim, Yong Jae Lee, Jinwook Hwang, Hyeyoung Yeom, Soumya Upadhyay, Caroline Liu, Haneul Choi, Ji Won Yoo

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Heart failure (HF) remains the most common diagnosis of hospital admission among U.S. adults. Although diagnosis and treatment have improved, mortality rates have not changed, and mortality risk remains high after hospitalization. The current researchers examined how limited health literacy is associated with mortality risk in adults with recent hospitalization due to decompensated HF. Researchers conducted a systematic literature search, selecting three cohort and three intervention studies. The fixed-effect model was used. From the three cohort studies, 2,858 study participants were analyzed. Among participants, limited health literacy was associated with higher all-cause mortality (pooled odds ratio = 2.95; 95% confidence interval [2.34, 3.72]; p < 0.01; I 2 = 47.38%). However, none of the intervention studies showed an association between limited health literacy and cardiac (or all-cause) mortality. Future research should focus on the efficiency and safety of telehealth-based medicine in patients with HF, particularly those with limited health literacy.

Original languageEnglish
Pages (from-to)99-108
Number of pages10
JournalResearch in Gerontological Nursing
Issue number2
Publication statusPublished - 2019 Mar 1

Bibliographical note

Funding Information:
The authors have disclosed no potential conflicts of interest,financial or otherwise.Dr.Yoo is supported by the faculty career development award from University of Nevada School of Medicine,Las Vegas,Nevada,and Dr.Kim is supported by Soonchunhyang University,Asan,Korea. Address correspondence to Ji Won Yoo, MD, MS, Assistant Professor, Department of Internal Medicine, University of Nevada Las Vegas School of Medicine, 1701 West Charleston Boulevard, #230, Las Vegas, NV 89102; e-mail: Received: April 4,2018; Accepted: August 17,2018 doi:10.3928/19404921-20181018-01

Publisher Copyright:
© SLACK Incorporated.

All Science Journal Classification (ASJC) codes

  • Nursing(all)
  • Gerontology
  • Health Policy
  • Geriatrics and Gerontology

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