Health-related quality of life of children with pre-dialysis chronic kidney disease

Hee Sun Baek, Hee Gyung Kang, Hyun Jin Choi, Hae Il Cheong, Il Soo Ha, Kyung Hee Han, Seong Heon Kim, Hee Yeon Cho, Jae Il Shin, Young Seo Park, Joo Hoon Lee, Joongyub Lee, Curie Ahn, Min Hyun Cho

Research output: Contribution to journalArticle

Abstract

Background: The goal of this study was to evaluate the quality of life (QOL) of Asian children with pre-dialysis chronic kidney disease (CKD) and to reveal the factors influencing the QOL of children with CKD. Methods: We performed a cross-sectional study of the PedsQL 4.0 Generic Core Scale Module in the KNOW-PedCKD (KoreaN cohort study for Outcome in patients with Pediatric Chronic Kidney Disease) cohort, and compared the child self-reported and parent proxy-reported QOL of the pediatric cohort. From 2011 through 2016, a total of 376 children with CKD were enrolled after informed consent was obtained from parents or caregivers in seven pediatric nephrology centers. Results: In parent proxy-reports, male patients had a better QOL than female patients in the Physical Functioning category. In child self-reports, male patients had better QOL than female patients in the Physical, Emotional, and School Functioning categories. According to CKD stage, there were significant differences in the QOL score in all categories of parent proxy-reports, and patients with higher CKD stage (lower glomerular filtration rate) had a worse QOL. Growth parameters showed a significantly positive correlation with the QOL score in all categories. Conclusions: The QOL of children with predialysis CKD is affected by various factors, including sex, glomerular filtration rate (GFR), socio-economic status, existence of co-morbidities, anemia, growth retardation, and behavioral disorders. To improve their QOL, it is important to objectively understand the respective effects of these factors and attempt early intervention.

Original languageEnglish
Pages (from-to)2097-2105
Number of pages9
JournalPediatric Nephrology
Volume32
Issue number11
DOIs
Publication statusPublished - 2017 Nov 1

Fingerprint

Chronic Renal Insufficiency
Dialysis
Quality of Life
Proxy
Pediatrics
Glomerular Filtration Rate
Sex Factors
Nephrology
Growth
Informed Consent
Self Report
Caregivers
Anemia
Cohort Studies
Cross-Sectional Studies
Parents
Economics
Morbidity

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Nephrology

Cite this

Baek, H. S., Kang, H. G., Choi, H. J., Cheong, H. I., Ha, I. S., Han, K. H., ... Cho, M. H. (2017). Health-related quality of life of children with pre-dialysis chronic kidney disease. Pediatric Nephrology, 32(11), 2097-2105. https://doi.org/10.1007/s00467-017-3721-5
Baek, Hee Sun ; Kang, Hee Gyung ; Choi, Hyun Jin ; Cheong, Hae Il ; Ha, Il Soo ; Han, Kyung Hee ; Kim, Seong Heon ; Cho, Hee Yeon ; Shin, Jae Il ; Park, Young Seo ; Lee, Joo Hoon ; Lee, Joongyub ; Ahn, Curie ; Cho, Min Hyun. / Health-related quality of life of children with pre-dialysis chronic kidney disease. In: Pediatric Nephrology. 2017 ; Vol. 32, No. 11. pp. 2097-2105.
@article{418b47a659be416da504dbc3f5db5f4b,
title = "Health-related quality of life of children with pre-dialysis chronic kidney disease",
abstract = "Background: The goal of this study was to evaluate the quality of life (QOL) of Asian children with pre-dialysis chronic kidney disease (CKD) and to reveal the factors influencing the QOL of children with CKD. Methods: We performed a cross-sectional study of the PedsQL 4.0 Generic Core Scale Module in the KNOW-PedCKD (KoreaN cohort study for Outcome in patients with Pediatric Chronic Kidney Disease) cohort, and compared the child self-reported and parent proxy-reported QOL of the pediatric cohort. From 2011 through 2016, a total of 376 children with CKD were enrolled after informed consent was obtained from parents or caregivers in seven pediatric nephrology centers. Results: In parent proxy-reports, male patients had a better QOL than female patients in the Physical Functioning category. In child self-reports, male patients had better QOL than female patients in the Physical, Emotional, and School Functioning categories. According to CKD stage, there were significant differences in the QOL score in all categories of parent proxy-reports, and patients with higher CKD stage (lower glomerular filtration rate) had a worse QOL. Growth parameters showed a significantly positive correlation with the QOL score in all categories. Conclusions: The QOL of children with predialysis CKD is affected by various factors, including sex, glomerular filtration rate (GFR), socio-economic status, existence of co-morbidities, anemia, growth retardation, and behavioral disorders. To improve their QOL, it is important to objectively understand the respective effects of these factors and attempt early intervention.",
author = "Baek, {Hee Sun} and Kang, {Hee Gyung} and Choi, {Hyun Jin} and Cheong, {Hae Il} and Ha, {Il Soo} and Han, {Kyung Hee} and Kim, {Seong Heon} and Cho, {Hee Yeon} and Shin, {Jae Il} and Park, {Young Seo} and Lee, {Joo Hoon} and Joongyub Lee and Curie Ahn and Cho, {Min Hyun}",
year = "2017",
month = "11",
day = "1",
doi = "10.1007/s00467-017-3721-5",
language = "English",
volume = "32",
pages = "2097--2105",
journal = "Pediatric Nephrology",
issn = "0931-041X",
publisher = "Springer Verlag",
number = "11",

}

Baek, HS, Kang, HG, Choi, HJ, Cheong, HI, Ha, IS, Han, KH, Kim, SH, Cho, HY, Shin, JI, Park, YS, Lee, JH, Lee, J, Ahn, C & Cho, MH 2017, 'Health-related quality of life of children with pre-dialysis chronic kidney disease', Pediatric Nephrology, vol. 32, no. 11, pp. 2097-2105. https://doi.org/10.1007/s00467-017-3721-5

Health-related quality of life of children with pre-dialysis chronic kidney disease. / Baek, Hee Sun; Kang, Hee Gyung; Choi, Hyun Jin; Cheong, Hae Il; Ha, Il Soo; Han, Kyung Hee; Kim, Seong Heon; Cho, Hee Yeon; Shin, Jae Il; Park, Young Seo; Lee, Joo Hoon; Lee, Joongyub; Ahn, Curie; Cho, Min Hyun.

In: Pediatric Nephrology, Vol. 32, No. 11, 01.11.2017, p. 2097-2105.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Health-related quality of life of children with pre-dialysis chronic kidney disease

AU - Baek, Hee Sun

AU - Kang, Hee Gyung

AU - Choi, Hyun Jin

AU - Cheong, Hae Il

AU - Ha, Il Soo

AU - Han, Kyung Hee

AU - Kim, Seong Heon

AU - Cho, Hee Yeon

AU - Shin, Jae Il

AU - Park, Young Seo

AU - Lee, Joo Hoon

AU - Lee, Joongyub

AU - Ahn, Curie

AU - Cho, Min Hyun

PY - 2017/11/1

Y1 - 2017/11/1

N2 - Background: The goal of this study was to evaluate the quality of life (QOL) of Asian children with pre-dialysis chronic kidney disease (CKD) and to reveal the factors influencing the QOL of children with CKD. Methods: We performed a cross-sectional study of the PedsQL 4.0 Generic Core Scale Module in the KNOW-PedCKD (KoreaN cohort study for Outcome in patients with Pediatric Chronic Kidney Disease) cohort, and compared the child self-reported and parent proxy-reported QOL of the pediatric cohort. From 2011 through 2016, a total of 376 children with CKD were enrolled after informed consent was obtained from parents or caregivers in seven pediatric nephrology centers. Results: In parent proxy-reports, male patients had a better QOL than female patients in the Physical Functioning category. In child self-reports, male patients had better QOL than female patients in the Physical, Emotional, and School Functioning categories. According to CKD stage, there were significant differences in the QOL score in all categories of parent proxy-reports, and patients with higher CKD stage (lower glomerular filtration rate) had a worse QOL. Growth parameters showed a significantly positive correlation with the QOL score in all categories. Conclusions: The QOL of children with predialysis CKD is affected by various factors, including sex, glomerular filtration rate (GFR), socio-economic status, existence of co-morbidities, anemia, growth retardation, and behavioral disorders. To improve their QOL, it is important to objectively understand the respective effects of these factors and attempt early intervention.

AB - Background: The goal of this study was to evaluate the quality of life (QOL) of Asian children with pre-dialysis chronic kidney disease (CKD) and to reveal the factors influencing the QOL of children with CKD. Methods: We performed a cross-sectional study of the PedsQL 4.0 Generic Core Scale Module in the KNOW-PedCKD (KoreaN cohort study for Outcome in patients with Pediatric Chronic Kidney Disease) cohort, and compared the child self-reported and parent proxy-reported QOL of the pediatric cohort. From 2011 through 2016, a total of 376 children with CKD were enrolled after informed consent was obtained from parents or caregivers in seven pediatric nephrology centers. Results: In parent proxy-reports, male patients had a better QOL than female patients in the Physical Functioning category. In child self-reports, male patients had better QOL than female patients in the Physical, Emotional, and School Functioning categories. According to CKD stage, there were significant differences in the QOL score in all categories of parent proxy-reports, and patients with higher CKD stage (lower glomerular filtration rate) had a worse QOL. Growth parameters showed a significantly positive correlation with the QOL score in all categories. Conclusions: The QOL of children with predialysis CKD is affected by various factors, including sex, glomerular filtration rate (GFR), socio-economic status, existence of co-morbidities, anemia, growth retardation, and behavioral disorders. To improve their QOL, it is important to objectively understand the respective effects of these factors and attempt early intervention.

UR - http://www.scopus.com/inward/record.url?scp=85022020087&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85022020087&partnerID=8YFLogxK

U2 - 10.1007/s00467-017-3721-5

DO - 10.1007/s00467-017-3721-5

M3 - Article

C2 - 28685173

AN - SCOPUS:85022020087

VL - 32

SP - 2097

EP - 2105

JO - Pediatric Nephrology

JF - Pediatric Nephrology

SN - 0931-041X

IS - 11

ER -