Abstract
A series of nylon-like oligomers was synthesized, which consisted of alternating cyclic 1,2-diamine and 1,2-dicarboxylic acid building blocks with a five-membered ring constraint. The nylon 2 4 oligomers are symmetric and display helical structures similar to the β-peptide 12-helix with intramolecular 12-membered ring hydrogen bonds. The cyclopentane moiety allows each building block to promote 12-helical folding. In addition, a tartaric acid derivative with the acetonide moiety increases the solubility of oligomers in common organic solvents and promotes helical folding.
| Original language | English |
|---|---|
| Pages (from-to) | 1069-1073 |
| Number of pages | 5 |
| Journal | ChemPlusChem |
| Volume | 86 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2021 Aug |
Bibliographical note
Funding Information:This study was supported by the National Research Foundation of Korea (NRF-2020R1F1 A1075279, NRF-2021R1 A2 C1013477). High-field NMR data were acquired at the Korea Basic Science Institute (Western Seoul). Bruker SMART APEX2 was purchased by UW-Madison Department of Chemistry with a portion of a generous gift from Paul J. and Margaret M. Bender.
Funding Information:
This study was supported by the National Research Foundation of Korea (NRF‐2020R1F1 A1075279, NRF‐2021R1 A2 C1013477). High‐field NMR data were acquired at the Korea Basic Science Institute (Western Seoul). Bruker SMART APEX2 was purchased by UW‐Madison Department of Chemistry with a portion of a generous gift from Paul J. and Margaret M. Bender.
Publisher Copyright:
© 2021 Wiley-VCH GmbH
All Science Journal Classification (ASJC) codes
- Chemistry(all)