Hemorrhagic transformation of ischemic stroke: Severe complications of prosthetic valve endocarditis

Jin Sun Kim, Woo In Yang, Chi Young Shim, Jong Won Ha, Namsik Chung, Hyuk Jae Chang

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Ischemic stroke is a common complication of infective endocarditis (IE), occurring in 20-40% of left side IE cases. In these subsets, anticoagulation therapy may provoke hemorrhagic transformation (HT) of ischemic stroke, and complications of this magnitude deteriorate the clinical course for IE patients. However, in cases of IE complicated with a mechanical prosthetic valve, the physician can be concerned over the maintenance of anticoagulation due to the risk of thrombotic complication. According to our retrospective review, HT of ischemic stroke in prosthetic valve endocarditis occurred 13.8% (4/29) of the time in a variety of situations. Some of these even arose in patients with a subtherapeutic range of prothrombin time.

Original languageEnglish
Pages (from-to)490-493
Number of pages4
JournalKorean Circulation Journal
Volume41
Issue number8
DOIs
Publication statusPublished - 2011 Aug 1

Fingerprint

Endocarditis
Stroke
Prothrombin Time
Maintenance
Physicians
Therapeutics

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Hemorrhagic transformation of ischemic stroke: Severe complications of prosthetic valve endocarditis",
abstract = "Ischemic stroke is a common complication of infective endocarditis (IE), occurring in 20-40{\%} of left side IE cases. In these subsets, anticoagulation therapy may provoke hemorrhagic transformation (HT) of ischemic stroke, and complications of this magnitude deteriorate the clinical course for IE patients. However, in cases of IE complicated with a mechanical prosthetic valve, the physician can be concerned over the maintenance of anticoagulation due to the risk of thrombotic complication. According to our retrospective review, HT of ischemic stroke in prosthetic valve endocarditis occurred 13.8{\%} (4/29) of the time in a variety of situations. Some of these even arose in patients with a subtherapeutic range of prothrombin time.",
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Hemorrhagic transformation of ischemic stroke : Severe complications of prosthetic valve endocarditis. / Kim, Jin Sun; Yang, Woo In; Shim, Chi Young; Ha, Jong Won; Chung, Namsik; Chang, Hyuk Jae.

In: Korean Circulation Journal, Vol. 41, No. 8, 01.08.2011, p. 490-493.

Research output: Contribution to journalArticle

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AU - Kim, Jin Sun

AU - Yang, Woo In

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AU - Ha, Jong Won

AU - Chung, Namsik

AU - Chang, Hyuk Jae

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