Novel approaches using bioactive molecules in the purpose for overcoming the limitation of established materials have been studied. Their ultimate goal is focused on improved blood/cell compatible biomaterials for various biomedical applications. Heparin-bound bioactive materials using bovine pericardium have been developed. From results of heparinized cellular or acellular tissue matrices, the effect of heparin on the tissue in cell-related biological responses as well as improved blood compatibility was confirmed. These heparinized matrices can be useful for tissue regeneration through the control of growth factor in tissue engineering as well as cardiovascular application.
All Science Journal Classification (ASJC) codes
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering