This research presents the development of neural electrodes with a high charge storage capacity using electrodeposited iridium oxide ilm (EIROF). The neural electrode was fabricated on a lexible liquid crystal polymer (LCP) substrate, which has a low moisture absorption rate and a low moisture permeability. On the electrode sites, iridium oxide was electrodeposited to increase the charge storage capacity for facilitating both neural stimulation and neural recording. Although EIROFs have been previously proposed as an electrode material, the fabrication process was not thoroughly investigated and optimized.(20) After electrodeposition using different numbers of rectangular voltage pulses and triangular waveforms, the iridium oxide electrodes were characterized in terms of charge storage capacity and electrochemical impedance. The surfaces of EIROFs were examined using atomic force microscopy (AFM) and scanning electron microscopy (SEM). In addition, the elementary composition of the EIROF surfaces was quantitatively determined using X-ray photoelectron spectroscopy (XPS). The in vivo neural recording from the rat ventral poster lateral (VPL) nucleus successfully showed that the proposed electrode is feasible for recording the neural activity.
Bibliographical noteFunding Information:
This work was supported in part by the Pioneer Research Center Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (NRF- 2009-0082961); in part by the Public Welfare & Safety Research Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (NRF-2010-0020851, NRF-2014R1A1A1A05003770); in part by the Center for Integrated Smart Sensors as GFP (CISS-2012M3A6A6054204); in part by an engineering-dentistry interdisciplinary research grant jointly funded by the College of Engineering and the College of Dentistry, Seoul National University; in part by the BK21 Plus Project, Department of Electrical and Computer Engineering, SNU, in 2015; in part by Business for Cooperative R&D between Industry, Academy, and Research Institute funded Korea Small and Medium Business Administration in 2015 (C0275626); and in part by a grant to CABMC (Control of Animal Brain using MEMS Chip) funded by Defense Acquisition Program Administration (UD140069ID).
All Science Journal Classification (ASJC) codes
- Materials Science(all)