Nonlinear optical microcopy has become an important tool in investigating biomaterials due to its various advantages such as label-free imaging capabilities. In particular, it has been shown that third-harmonic generation (THG) signals can be produced at interfaces between an aqueous medium (e.g. cytoplasm, interstitial fluid) and a mineralized lipidic surface. In this work, we have demonstrated that label-free high-contrast THG images of the mycobacterium tuberculosis can be obtained using THG microscopy.
|Title of host publication||International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy 2015, NBSIS 2015|
|Editors||Donghyun Kim, Min-Gon Kim, Seung-Han Park|
|Publication status||Published - 2015|
|Event||2nd International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy, NBSIS 2015 - Jeju, Korea, Republic of|
Duration: 2015 Feb 25 → 2015 Feb 27
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Other||2nd International Conference on Nano-Bio Sensing, Imaging, and Spectroscopy, NBSIS 2015|
|Country||Korea, Republic of|
|Period||15/2/25 → 15/2/27|
Bibliographical notePublisher Copyright:
© 2015 SPIE.
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging