High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

Yoonkyung Kim; Hye Youn Jung; Yun Hui Choe; Chaewoon Lee; Sung Kyun Ko; Soonil Koun; Yohan Choi; Bong Hyun Chung; Byoung Chul Park; Tae Lin Huh; Injae Shin; Eunkyoung Kim

doi:10.1002/anie.201107086

High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

Yoonkyung Kim, Hye Youn Jung, Yun Hui Choe, Chaewoon Lee, Sung Kyun Ko, Soonil Koun, Yohan Choi, Bong Hyun Chung, Byoung Chul Park, Tae Lin Huh, Injae Shin, Eunkyoung Kim

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.

Original language	English
Pages (from-to)	2878-2882
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	12
DOIs	https://doi.org/10.1002/anie.201107086
Publication status	Published - 2012 Mar 19

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

Access to Document

10.1002/anie.201107086

Cite this

Kim, Yoonkyung ; Jung, Hye Youn ; Choe, Yun Hui ; Lee, Chaewoon ; Ko, Sung Kyun ; Koun, Soonil ; Choi, Yohan ; Chung, Bong Hyun ; Park, Byoung Chul ; Huh, Tae Lin ; Shin, Injae ; Kim, Eunkyoung. / High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates. In: Angewandte Chemie - International Edition. 2012 ; Vol. 51, No. 12. pp. 2878-2882.

@article{1e7bd0add24b4567b685f19421d22dfa,

title = "High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates",

abstract = "Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.",

author = "Yoonkyung Kim and Jung, {Hye Youn} and Choe, {Yun Hui} and Chaewoon Lee and Ko, {Sung Kyun} and Soonil Koun and Yohan Choi and Chung, {Bong Hyun} and Park, {Byoung Chul} and Huh, {Tae Lin} and Injae Shin and Eunkyoung Kim",

year = "2012",

month = mar,

day = "19",

doi = "10.1002/anie.201107086",

language = "English",

volume = "51",

pages = "2878--2882",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "12",

}

High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates. / Kim, Yoonkyung; Jung, Hye Youn; Choe, Yun Hui; Lee, Chaewoon; Ko, Sung Kyun; Koun, Soonil; Choi, Yohan; Chung, Bong Hyun; Park, Byoung Chul; Huh, Tae Lin; Shin, Injae ; Kim, Eunkyoung.

In: Angewandte Chemie - International Edition, Vol. 51, No. 12, 19.03.2012, p. 2878-2882.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

AU - Kim, Yoonkyung

AU - Jung, Hye Youn

AU - Choe, Yun Hui

AU - Lee, Chaewoon

AU - Ko, Sung Kyun

AU - Koun, Soonil

AU - Choi, Yohan

AU - Chung, Bong Hyun

AU - Park, Byoung Chul

AU - Huh, Tae Lin

AU - Shin, Injae

AU - Kim, Eunkyoung

PY - 2012/3/19

Y1 - 2012/3/19

N2 - Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.

AB - Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.

UR - http://www.scopus.com/inward/record.url?scp=84863253096&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863253096&partnerID=8YFLogxK

U2 - 10.1002/anie.201107086

DO - 10.1002/anie.201107086

M3 - Article

C2 - 22307986

AN - SCOPUS:84863253096

VL - 51

SP - 2878

EP - 2882

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

SN - 1433-7851

IS - 12

ER -

High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this