High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

Yoonkyung Kim; Hye Youn Jung; Yun Hui Choe; Chaewoon Lee; Sung Kyun Ko; Soonil Koun; Yohan Choi; Bong Hyun Chung; Byoung Chul Park; Tae Lin Huh; Injae Shin; Eunkyoung Kim

doi:10.1002/anie.201107086

High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

Yoonkyung Kim, Hye Youn Jung, Yun Hui Choe, Chaewoon Lee, Sung Kyun Ko, Soonil Koun, Yohan Choi, Bong Hyun Chung, Byoung Chul Park, Tae Lin Huh, Injae Shin, Eunkyoung Kim

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.

Original language	English
Pages (from-to)	2878-2882
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	12
DOIs	https://doi.org/10.1002/anie.201107086
Publication status	Published - 2012 Mar 19

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

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title = "High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates",

abstract = "Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.",

author = "Yoonkyung Kim and Jung, {Hye Youn} and Choe, {Yun Hui} and Chaewoon Lee and Ko, {Sung Kyun} and Soonil Koun and Yohan Choi and Chung, {Bong Hyun} and Park, {Byoung Chul} and Huh, {Tae Lin} and Injae Shin and Eunkyoung Kim",

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doi = "10.1002/anie.201107086",

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T1 - High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

AU - Kim, Yoonkyung

AU - Jung, Hye Youn

AU - Choe, Yun Hui

AU - Lee, Chaewoon

AU - Ko, Sung Kyun

AU - Koun, Soonil

AU - Choi, Yohan

AU - Chung, Bong Hyun

AU - Park, Byoung Chul

AU - Huh, Tae Lin

AU - Shin, Injae

AU - Kim, Eunkyoung

PY - 2012/3/19

Y1 - 2012/3/19

N2 - Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.

AB - Dendrimers crosslinked with a photochromic diarylethene (blue in picture) were labeled with the fluorescent dye Cy3 (red) for reversible fluorescence photoswitching. If the obtained nanoclusters are irradiated with UV light, the Cy3 fluorescence is quenched by the diarylethene in its ring-closed form, whereas upon irradiation with visible light, the nanoclusters show fluorescence. High-contrast fluorescence imaging was achieved inside a living zebrafish.

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High-contrast reversible fluorescence photoswitching of dye-crosslinked dendritic nanoclusters in living vertebrates

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