High peritoneal transport status is not an independent risk factor for high mortality in patients treated with automated peritoneal dialysis

Tae Ik Chang, Jung Tak Park, Dong Hyung Lee, Ju Hyun Lee, TaeHyun Yoo, Beom Seok Kim, Shin-Wook Kang, Ho Yung Lee, Kyu Hun Choi

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Abstract

We undertook this study to elucidate whether baseline peritoneal membrane transport characteristics are associated with high mortality in incident automated peritoneal dialysis (APD) patients. This retrospective study includes 117 patients who started APD at Yonsei University Health System from 1996 to 2008 and had a PET within 3 months of APD initiation. High transporters were significantly older and had a higher incidence of cardiovascular disease. Patient survival for years 1, 3, and 5 were 85%, 64%, and 35% for high transporter and 94%, 81%, and 68% for non-high transporter group (P<0.01). Multivariate analysis revealed that age, diabetes, cardiovascular disease, serum albumin level, and residual renal function were independently associated with high mortality in APD patients. In contrast, high transport status was not a significant predictor for mortality in this population when the other covariates were included. Even though high transport was significantly associated with mortality in the univariate analysis, its role seemed to be influenced by other comorbid conditions. These findings suggest that the proper management of these comorbid conditions, as well as appropriate ultrafiltration by use of APD and/or icodextrin, must be considered as protective strategies to improve survival in peritoneal dialysis patients with high transport.

Original languageEnglish
Pages (from-to)1313-1317
Number of pages5
JournalJournal of Korean medical science
Volume25
Issue number9
DOIs
Publication statusPublished - 2010 Sep 1

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Peritoneal Dialysis
Mortality
Cardiovascular Diseases
Survival
Ultrafiltration
Serum Albumin
Multivariate Analysis
Retrospective Studies
Kidney
Membranes
Incidence
Health
Population

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Chang, Tae Ik ; Park, Jung Tak ; Lee, Dong Hyung ; Lee, Ju Hyun ; Yoo, TaeHyun ; Kim, Beom Seok ; Kang, Shin-Wook ; Lee, Ho Yung ; Choi, Kyu Hun. / High peritoneal transport status is not an independent risk factor for high mortality in patients treated with automated peritoneal dialysis. In: Journal of Korean medical science. 2010 ; Vol. 25, No. 9. pp. 1313-1317.
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High peritoneal transport status is not an independent risk factor for high mortality in patients treated with automated peritoneal dialysis. / Chang, Tae Ik; Park, Jung Tak; Lee, Dong Hyung; Lee, Ju Hyun; Yoo, TaeHyun; Kim, Beom Seok; Kang, Shin-Wook; Lee, Ho Yung; Choi, Kyu Hun.

In: Journal of Korean medical science, Vol. 25, No. 9, 01.09.2010, p. 1313-1317.

Research output: Contribution to journalArticle

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AU - Kim, Beom Seok

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AU - Lee, Ho Yung

AU - Choi, Kyu Hun

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