High prevalence of ceftazidime-resistant Klebsiella pneumoniae and increase of imipenem-resistant Pseudomonas aeruginosa and Acinetobacter spp. in Korea: A KONSAR Program in 2004

Kyungwon Lee, Chang Hyun Lim, Ji Hyun Cho, Wee Gyo Lee, Young Uh, Hwi Jun Kim, Dongeun Yong, Yunsop Chong, Jae Seok Kim, Sunjoo Kim, Namhee Ryoo, Seok Hoon Jeong, Mun Yeun Kim, Gyoung Yim Ha, Chulhun L. Chang, Ki Hyung Park, Mi Na Kim, Myungshin Kim, Jeong Ho Kim, Joseph JeongSeok Il Ilong, Soung Eun Cho, Jin Ju Kim, Hye Soo Lee, Sook Jin Jang, Ae Ja Park, Young Joo Cha, Dong Hoon Shin, Sun Hoe Koo, Myung Hee Lee, Wonkeun Song, Tae Yeal Choi, Eui Chong Kim, Jung Oak Kang, Yeon Joon Park, Jong Hee Shin, Seong Geun Hong, Young Ah Kim, Hee Joo Lee, Dong Hee Cho, Hwan Sub Lim, Miae Lee, Hee Bong Shin, Young Ree Kim, Seung Ok Lee, Sung Hee Lee, Seong Gyu Lee

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37 Citations (Scopus)

Abstract

A nationwide antimicrobial resistance surveillance has been conducted since 1997 in Korea. In this study, susceptibility test data generated in 2004 by KONSAR group hospitals were analyzed and compared to those at a commercial laboratory. In hospitals, the rank orders of organisms in 2004 were identical to those in 2003. The most prevalent species was Staphylococcus aureus (20.2%) in hospitals, but Evcherichia coli (29.7%) in the commercial laboratory. The proportions of Enterococcus faecium to all isolates of Enterococcus faecalis plus E. faecium were 47.2% in hospitals and 24.9% in the commercial laboratory, The mean resistance rates of significant antimicrobial-organism combinations in hospitals were: oxaciltin-resistant S. aureus (68%), oxacillin-resistant (penicillin-nonsusceptible) Streptococcus pneumoniae (68%), vancomycin-resistant E. faecium (25%), cefotaxime-resistant E. coli (14%), ceftazidime- and cefoxitin-resistant Klebsiella pneumoniae (34% and 32%, respectively), and imipenem-resistant Acinetobacter spp. and Pseudomonas aeruginosa (17% and 24%, respectively). In conclusion, oxacillin-resistant staphylococci, expanded-spectrum cephalosporin-resistant K. pneumoniae, and imipenem-resistant Acinetobacter spp. and P. aeruginosa were prevalent in 2004. Increasing trends were observed for vancomycin-resistant E. faecium, cefoxitin-resistant E. coli and K. pneumoniae, and imipenem-resistant Acinetobacter spp. and P. aeruginosa. Certain antimicrobial-organism combinations were also prevalent among the commercial taboratoly-tested stains.

Original languageEnglish
Pages (from-to)634-645
Number of pages12
JournalYonsei medical journal
Volume47
Issue number5
DOIs
Publication statusPublished - 2006 Oct

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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