High suspicion US pattern on the ATA guidelines, not cytologic diagnosis, may be a predicting marker of lymph node metastasis in patients with classical papillary thyroid carcinoma

Eun Cho, Eun Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Y. Park, Jin Young Kwak

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2 Citations (Scopus)

Abstract

Background: To evaluate the utility of ultrasound (US) patterns based on the 2015 American Thyroid Association (ATA) guidelines and cytologic diagnosis of the Bethesda System for Reporting Thyroid Cytopathology as predicting markers for lymph node metastasis (LNM) in classical papillary thyroid carcinoma (PTC). Methods: A retrospective analysis of 657 patients with classical PTC who underwent ultrasound-guided fine-needle aspiration (US-FNA) and surgery were included in this study. The associations between LNM and the US features or the Bethesda System for Reporting Thyroid Cytopathology were evaluated. Results: Multivariate logistic regression analysis showed that the high suspicion US pattern was independently associated with LNM (odds ratio = 3.081; 95% confidence interval = 1.515–6.262; P =.002). And the Bethesda category was not significantly associated with LNM (P =.056). Conclusions: The high suspicion US pattern of the 2015 ATA guidelines, not cytologic diagnosis, could be a predicting marker of LNM in patients with classical PTC.

Original languageEnglish
Pages (from-to)562-566
Number of pages5
JournalAmerican Journal of Surgery
Volume216
Issue number3
DOIs
Publication statusPublished - 2018 Sep

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Thyroid Gland
Lymph Nodes
Guidelines
Neoplasm Metastasis
Fine Needle Biopsy
Logistic Models
Odds Ratio
Regression Analysis
Papillary Thyroid cancer
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

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title = "High suspicion US pattern on the ATA guidelines, not cytologic diagnosis, may be a predicting marker of lymph node metastasis in patients with classical papillary thyroid carcinoma",
abstract = "Background: To evaluate the utility of ultrasound (US) patterns based on the 2015 American Thyroid Association (ATA) guidelines and cytologic diagnosis of the Bethesda System for Reporting Thyroid Cytopathology as predicting markers for lymph node metastasis (LNM) in classical papillary thyroid carcinoma (PTC). Methods: A retrospective analysis of 657 patients with classical PTC who underwent ultrasound-guided fine-needle aspiration (US-FNA) and surgery were included in this study. The associations between LNM and the US features or the Bethesda System for Reporting Thyroid Cytopathology were evaluated. Results: Multivariate logistic regression analysis showed that the high suspicion US pattern was independently associated with LNM (odds ratio = 3.081; 95{\%} confidence interval = 1.515–6.262; P =.002). And the Bethesda category was not significantly associated with LNM (P =.056). Conclusions: The high suspicion US pattern of the 2015 ATA guidelines, not cytologic diagnosis, could be a predicting marker of LNM in patients with classical PTC.",
author = "Eun Cho and Kim, {Eun Kyung} and Moon, {Hee Jung} and Yoon, {Jung Hyun} and Park, {Vivian Y.} and Kwak, {Jin Young}",
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language = "English",
volume = "216",
pages = "562--566",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
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TY - JOUR

T1 - High suspicion US pattern on the ATA guidelines, not cytologic diagnosis, may be a predicting marker of lymph node metastasis in patients with classical papillary thyroid carcinoma

AU - Cho, Eun

AU - Kim, Eun Kyung

AU - Moon, Hee Jung

AU - Yoon, Jung Hyun

AU - Park, Vivian Y.

AU - Kwak, Jin Young

PY - 2018/9

Y1 - 2018/9

N2 - Background: To evaluate the utility of ultrasound (US) patterns based on the 2015 American Thyroid Association (ATA) guidelines and cytologic diagnosis of the Bethesda System for Reporting Thyroid Cytopathology as predicting markers for lymph node metastasis (LNM) in classical papillary thyroid carcinoma (PTC). Methods: A retrospective analysis of 657 patients with classical PTC who underwent ultrasound-guided fine-needle aspiration (US-FNA) and surgery were included in this study. The associations between LNM and the US features or the Bethesda System for Reporting Thyroid Cytopathology were evaluated. Results: Multivariate logistic regression analysis showed that the high suspicion US pattern was independently associated with LNM (odds ratio = 3.081; 95% confidence interval = 1.515–6.262; P =.002). And the Bethesda category was not significantly associated with LNM (P =.056). Conclusions: The high suspicion US pattern of the 2015 ATA guidelines, not cytologic diagnosis, could be a predicting marker of LNM in patients with classical PTC.

AB - Background: To evaluate the utility of ultrasound (US) patterns based on the 2015 American Thyroid Association (ATA) guidelines and cytologic diagnosis of the Bethesda System for Reporting Thyroid Cytopathology as predicting markers for lymph node metastasis (LNM) in classical papillary thyroid carcinoma (PTC). Methods: A retrospective analysis of 657 patients with classical PTC who underwent ultrasound-guided fine-needle aspiration (US-FNA) and surgery were included in this study. The associations between LNM and the US features or the Bethesda System for Reporting Thyroid Cytopathology were evaluated. Results: Multivariate logistic regression analysis showed that the high suspicion US pattern was independently associated with LNM (odds ratio = 3.081; 95% confidence interval = 1.515–6.262; P =.002). And the Bethesda category was not significantly associated with LNM (P =.056). Conclusions: The high suspicion US pattern of the 2015 ATA guidelines, not cytologic diagnosis, could be a predicting marker of LNM in patients with classical PTC.

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