Higher blood pressure variability in white coat hypertension; from the Korean Ambulatory Blood Pressure Monitoring Registry

In Sook Kang, Wook Bum Pyun, Jinho Shin, Sang Hyun Ihm, Ju Han Kim, Sungha Park, Kwang Il Kim, Woo Shik Kim, Soon Gil Kim, Gil Ja Shin

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background and Objectives: Blood pressure variability (BPV) was recently shown to be a risk factor of stroke. White coat hypertension (WCH) used to be regarded as innocuous, but one long-term follow-up study reported that WCH increased stroke rate compared to normotension (NT). In this study, we aimed to evaluate the relationship between WCH and BPV. Subjects and Methods: We analyzed 1398 subjects from the Korean Ambulatory Blood Pressure Registry, who were divided into NT (n=364), masked hypertension (n=122), white coat hypertension (n=254), and sustained hypertension (n=658) groups. Results: Baseline characteristics were similar among groups. The average real variability (ARV), a highly sensitive BPV parameter, was highest in the WCH group, followed by the sustained hypertension, masked hypertension, and NT groups. The results persisted after being adjusted for covariates. The WCH vs. sustained hypertension results (adjusted mean±standard error) were as follows: 24-h systolic ARV, 22.9±0.8 vs. 19.4±0.6; 24-h diastolic ARV, 16.8±0.6 vs. 14.3±0.5; daytime systolic ARV, 21.8±0.8 vs. 16.8±0.6; and daytime diastolic ARV, 16.2±0.6 vs. 13.4±0.5 (p<0.001 for all comparisons). Conclusion: From the registry data, we found that subjects with WCH or masked hypertension had higher BPV than NT. However, long-term follow-up data assessing the clinical influences of WCH on stroke are needed.

Original languageEnglish
Pages (from-to)365-373
Number of pages9
JournalKorean Circulation Journal
Volume46
Issue number3
DOIs
Publication statusPublished - 2016 May

Fingerprint

White Coat Hypertension
Ambulatory Blood Pressure Monitoring
Registries
Hypertension
Masked Hypertension
Blood Pressure
Stroke

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Kang, In Sook ; Pyun, Wook Bum ; Shin, Jinho ; Ihm, Sang Hyun ; Kim, Ju Han ; Park, Sungha ; Kim, Kwang Il ; Kim, Woo Shik ; Kim, Soon Gil ; Shin, Gil Ja. / Higher blood pressure variability in white coat hypertension; from the Korean Ambulatory Blood Pressure Monitoring Registry. In: Korean Circulation Journal. 2016 ; Vol. 46, No. 3. pp. 365-373.
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abstract = "Background and Objectives: Blood pressure variability (BPV) was recently shown to be a risk factor of stroke. White coat hypertension (WCH) used to be regarded as innocuous, but one long-term follow-up study reported that WCH increased stroke rate compared to normotension (NT). In this study, we aimed to evaluate the relationship between WCH and BPV. Subjects and Methods: We analyzed 1398 subjects from the Korean Ambulatory Blood Pressure Registry, who were divided into NT (n=364), masked hypertension (n=122), white coat hypertension (n=254), and sustained hypertension (n=658) groups. Results: Baseline characteristics were similar among groups. The average real variability (ARV), a highly sensitive BPV parameter, was highest in the WCH group, followed by the sustained hypertension, masked hypertension, and NT groups. The results persisted after being adjusted for covariates. The WCH vs. sustained hypertension results (adjusted mean±standard error) were as follows: 24-h systolic ARV, 22.9±0.8 vs. 19.4±0.6; 24-h diastolic ARV, 16.8±0.6 vs. 14.3±0.5; daytime systolic ARV, 21.8±0.8 vs. 16.8±0.6; and daytime diastolic ARV, 16.2±0.6 vs. 13.4±0.5 (p<0.001 for all comparisons). Conclusion: From the registry data, we found that subjects with WCH or masked hypertension had higher BPV than NT. However, long-term follow-up data assessing the clinical influences of WCH on stroke are needed.",
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Higher blood pressure variability in white coat hypertension; from the Korean Ambulatory Blood Pressure Monitoring Registry. / Kang, In Sook; Pyun, Wook Bum; Shin, Jinho; Ihm, Sang Hyun; Kim, Ju Han; Park, Sungha; Kim, Kwang Il; Kim, Woo Shik; Kim, Soon Gil; Shin, Gil Ja.

In: Korean Circulation Journal, Vol. 46, No. 3, 05.2016, p. 365-373.

Research output: Contribution to journalArticle

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AU - Pyun, Wook Bum

AU - Shin, Jinho

AU - Ihm, Sang Hyun

AU - Kim, Ju Han

AU - Park, Sungha

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AU - Kim, Woo Shik

AU - Kim, Soon Gil

AU - Shin, Gil Ja

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N2 - Background and Objectives: Blood pressure variability (BPV) was recently shown to be a risk factor of stroke. White coat hypertension (WCH) used to be regarded as innocuous, but one long-term follow-up study reported that WCH increased stroke rate compared to normotension (NT). In this study, we aimed to evaluate the relationship between WCH and BPV. Subjects and Methods: We analyzed 1398 subjects from the Korean Ambulatory Blood Pressure Registry, who were divided into NT (n=364), masked hypertension (n=122), white coat hypertension (n=254), and sustained hypertension (n=658) groups. Results: Baseline characteristics were similar among groups. The average real variability (ARV), a highly sensitive BPV parameter, was highest in the WCH group, followed by the sustained hypertension, masked hypertension, and NT groups. The results persisted after being adjusted for covariates. The WCH vs. sustained hypertension results (adjusted mean±standard error) were as follows: 24-h systolic ARV, 22.9±0.8 vs. 19.4±0.6; 24-h diastolic ARV, 16.8±0.6 vs. 14.3±0.5; daytime systolic ARV, 21.8±0.8 vs. 16.8±0.6; and daytime diastolic ARV, 16.2±0.6 vs. 13.4±0.5 (p<0.001 for all comparisons). Conclusion: From the registry data, we found that subjects with WCH or masked hypertension had higher BPV than NT. However, long-term follow-up data assessing the clinical influences of WCH on stroke are needed.

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