Higher-order aberration changes after Implantable Collamer Lens implantation for myopia

Sun Woong Kim, Hun Yang, Geunyoung Yoon, Yong Jun Lee, Mi Na Kweon, Jin Kook Kim, Kyoung Yul Seo

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26 Citations (Scopus)


Purpose: To investigate the changes in higher-order aberrations (HOAs) induced by implantation of Implantable Collamer Lenses (STAAR Surgical) and to explain them in relation to the surgical incision and optical properties. Design Prospective, observational case study. Methods This study included 56 eyes undergoing Implantable Collamer Lens insertion for myopic correction. The corneal incision size was determined according to the amount of astigmatism. HOAs were measured before surgery and 3 months after surgery in 25 eyes having small superior incision (<3.2 mm) surgery and in 31 eyes with large superior incision (3.2 to 4.5 mm) surgery. Changes in spherical aberration, coma, trefoil, and total HOAs (third to sixth order) were analyzed. Laboratory measurements of aberration profiles of Implantable Collamer Lenses with different optical powers were performed to validate clinical measurements. Results In the small-incision group, trefoil (Z3 -3) and spherical aberration changed significantly (P = .004). In the large-incision group, in addition to trefoil and spherical aberration, total HOA changed significantly (mean change, 0.13 ± 0.17; P = .001). Significant correlations were observed among the incision size, the astigmatism induced, and the trefoil induced. Induced trefoil showed a predominant pattern at the orientation of the incision meridian. Optical measurement of aberrations of the Implantable Collamer Lenses confirmed the postoperative negative spherical aberration. Conclusions HOA changes after Implantable Collamer Lens insertion were increased trefoil and induced negative spherical aberration. These changes may be explained by the effect of the corneal incision and the negative spherical aberration in the Implantable Collamer Lens, respectively.

Original languageEnglish
Pages (from-to)653-662.e1
JournalAmerican Journal of Ophthalmology
Issue number4
Publication statusPublished - 2011 Apr

Bibliographical note

Funding Information:
Publication of this article was supported by Grant A084790 from the Korea Healthcare Technology R&D Project , Ministry for Health, Welfare, and Family Affairs, Seoul, Republic of Korea. The authors indicate no financial conflicts of interest. All authors were involved in the Design and conduct of this study; Collection, management, analysis, and interpretation of data; and Preparation, review, and approval of the manuscript. This study protocol was approved by the Soonchunhyang University Institutional Review Board and was conducted according to the tenets of the Declaration of Helsinki. Written informed consent was obtained from each patient after they received an explanation of the nature and consequences of the procedures.

All Science Journal Classification (ASJC) codes

  • Ophthalmology


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