Abstract
This paper presents a microfluidic chip array for high-throughput single cell assay with an efficient cell capture rate. The single cell capture structure utilizes hydrodynamic resistance difference in flow paths and its feasibility was tested. More than 40% of all the injected microbeads were captured in the designated capture sites. The capture structure was expanded in an array of microwells formed at the intersection of rows and columns of orthogonal microchannels. By selectively operating integrated pneumatic valves, we successfully demonstrated cell seeding, reagents injection and cell isolation without cross-contamination.
Original language | English |
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Pages | 477-479 |
Number of pages | 3 |
Publication status | Published - 2008 |
Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16 |
Other
Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
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Country/Territory | United States |
City | San Diego, CA |
Period | 08/10/12 → 08/10/16 |
All Science Journal Classification (ASJC) codes
- Chemical Engineering (miscellaneous)
- Bioengineering