Highly selective catalytic Friedel-Crafts acylation and sulfonylation of activated aromatic compounds using indium metal

Doook Jang, Kyung Soo Moon, Dae Hyan Cho, Joong Gon Kim

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

The Friedel-Crafts acylation of activated benzenes with various aromatic and aliphatic acid chlorides was studied in the presence of indium metal. The reaction was accomplished in high isolated yields under solvent or solvent-less conditions. The method is also applicable for preparing diaryl sulfones from aromatic compounds and aryl sulfonyl chlorides.

Original languageEnglish
Pages (from-to)6063-6066
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number34
DOIs
Publication statusPublished - 2006 Aug 21

Fingerprint

Acylation
Indium
Aromatic compounds
Metals
Sulfones
Benzene
Chlorides
Fatty Acids
sulfonyl chloride

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Jang, Doook ; Moon, Kyung Soo ; Cho, Dae Hyan ; Kim, Joong Gon. / Highly selective catalytic Friedel-Crafts acylation and sulfonylation of activated aromatic compounds using indium metal. In: Tetrahedron Letters. 2006 ; Vol. 47, No. 34. pp. 6063-6066.
@article{805c180b9b7549b5887cbda07076c7e6,
title = "Highly selective catalytic Friedel-Crafts acylation and sulfonylation of activated aromatic compounds using indium metal",
abstract = "The Friedel-Crafts acylation of activated benzenes with various aromatic and aliphatic acid chlorides was studied in the presence of indium metal. The reaction was accomplished in high isolated yields under solvent or solvent-less conditions. The method is also applicable for preparing diaryl sulfones from aromatic compounds and aryl sulfonyl chlorides.",
author = "Doook Jang and Moon, {Kyung Soo} and Cho, {Dae Hyan} and Kim, {Joong Gon}",
year = "2006",
month = "8",
day = "21",
doi = "10.1016/j.tetlet.2006.06.099",
language = "English",
volume = "47",
pages = "6063--6066",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "34",

}

Highly selective catalytic Friedel-Crafts acylation and sulfonylation of activated aromatic compounds using indium metal. / Jang, Doook; Moon, Kyung Soo; Cho, Dae Hyan; Kim, Joong Gon.

In: Tetrahedron Letters, Vol. 47, No. 34, 21.08.2006, p. 6063-6066.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Highly selective catalytic Friedel-Crafts acylation and sulfonylation of activated aromatic compounds using indium metal

AU - Jang, Doook

AU - Moon, Kyung Soo

AU - Cho, Dae Hyan

AU - Kim, Joong Gon

PY - 2006/8/21

Y1 - 2006/8/21

N2 - The Friedel-Crafts acylation of activated benzenes with various aromatic and aliphatic acid chlorides was studied in the presence of indium metal. The reaction was accomplished in high isolated yields under solvent or solvent-less conditions. The method is also applicable for preparing diaryl sulfones from aromatic compounds and aryl sulfonyl chlorides.

AB - The Friedel-Crafts acylation of activated benzenes with various aromatic and aliphatic acid chlorides was studied in the presence of indium metal. The reaction was accomplished in high isolated yields under solvent or solvent-less conditions. The method is also applicable for preparing diaryl sulfones from aromatic compounds and aryl sulfonyl chlorides.

UR - http://www.scopus.com/inward/record.url?scp=33745979178&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745979178&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2006.06.099

DO - 10.1016/j.tetlet.2006.06.099

M3 - Article

AN - SCOPUS:33745979178

VL - 47

SP - 6063

EP - 6066

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 34

ER -