Highly selective catalytic Friedel-Crafts acylation and sulfonylation of activated aromatic compounds using indium metal

Doo Ok Jang, Kyung Soo Moon, Dae Hyan Cho, Joong Gon Kim

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

The Friedel-Crafts acylation of activated benzenes with various aromatic and aliphatic acid chlorides was studied in the presence of indium metal. The reaction was accomplished in high isolated yields under solvent or solvent-less conditions. The method is also applicable for preparing diaryl sulfones from aromatic compounds and aryl sulfonyl chlorides.

Original languageEnglish
Pages (from-to)6063-6066
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number34
DOIs
Publication statusPublished - 2006 Aug 21

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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