Human orbitofrontal-striatum functional connectivity modulates behavioral persistence

Young Chul Jung, Jeonghun Ku, Kee Namkoong, Wonho Lee, Sun I. Kim, Jae Jin Kim

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The degree at which individuals maintain behavioral strategies during uncertain conditions varies widely; however, the neural bases of these individual differences remain unclear. This study examines the functional connectivity of the orbitofrontal cortex during a decision-making task using functional magnetic resonance imaging. The strength of the functional connectivity observed between the medial orbitofrontal cortex and the nucleus accumbens was determined to be correlated with the number of persistent responses made during the decision-making task. It is proposed that top-down control of the orbitofrontal cortex over the ventral striatum is a critical component underlying individual differences in decision making during uncertain conditions.

Original languageEnglish
Pages (from-to)502-506
Number of pages5
JournalNeuroReport
Volume21
Issue number7
DOIs
Publication statusPublished - 2010 May 1

Fingerprint

Prefrontal Cortex
Decision Making
Individuality
Nucleus Accumbens
Magnetic Resonance Imaging

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Jung, Young Chul ; Ku, Jeonghun ; Namkoong, Kee ; Lee, Wonho ; Kim, Sun I. ; Kim, Jae Jin. / Human orbitofrontal-striatum functional connectivity modulates behavioral persistence. In: NeuroReport. 2010 ; Vol. 21, No. 7. pp. 502-506.
@article{3d8ae2caf79d40c297f7c3d38cdc1798,
title = "Human orbitofrontal-striatum functional connectivity modulates behavioral persistence",
abstract = "The degree at which individuals maintain behavioral strategies during uncertain conditions varies widely; however, the neural bases of these individual differences remain unclear. This study examines the functional connectivity of the orbitofrontal cortex during a decision-making task using functional magnetic resonance imaging. The strength of the functional connectivity observed between the medial orbitofrontal cortex and the nucleus accumbens was determined to be correlated with the number of persistent responses made during the decision-making task. It is proposed that top-down control of the orbitofrontal cortex over the ventral striatum is a critical component underlying individual differences in decision making during uncertain conditions.",
author = "Jung, {Young Chul} and Jeonghun Ku and Kee Namkoong and Wonho Lee and Kim, {Sun I.} and Kim, {Jae Jin}",
year = "2010",
month = "5",
day = "1",
doi = "10.1097/WNR.0b013e3283383482",
language = "English",
volume = "21",
pages = "502--506",
journal = "NeuroReport",
issn = "0959-4965",
publisher = "Lippincott Williams and Wilkins",
number = "7",

}

Human orbitofrontal-striatum functional connectivity modulates behavioral persistence. / Jung, Young Chul; Ku, Jeonghun; Namkoong, Kee; Lee, Wonho; Kim, Sun I.; Kim, Jae Jin.

In: NeuroReport, Vol. 21, No. 7, 01.05.2010, p. 502-506.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Human orbitofrontal-striatum functional connectivity modulates behavioral persistence

AU - Jung, Young Chul

AU - Ku, Jeonghun

AU - Namkoong, Kee

AU - Lee, Wonho

AU - Kim, Sun I.

AU - Kim, Jae Jin

PY - 2010/5/1

Y1 - 2010/5/1

N2 - The degree at which individuals maintain behavioral strategies during uncertain conditions varies widely; however, the neural bases of these individual differences remain unclear. This study examines the functional connectivity of the orbitofrontal cortex during a decision-making task using functional magnetic resonance imaging. The strength of the functional connectivity observed between the medial orbitofrontal cortex and the nucleus accumbens was determined to be correlated with the number of persistent responses made during the decision-making task. It is proposed that top-down control of the orbitofrontal cortex over the ventral striatum is a critical component underlying individual differences in decision making during uncertain conditions.

AB - The degree at which individuals maintain behavioral strategies during uncertain conditions varies widely; however, the neural bases of these individual differences remain unclear. This study examines the functional connectivity of the orbitofrontal cortex during a decision-making task using functional magnetic resonance imaging. The strength of the functional connectivity observed between the medial orbitofrontal cortex and the nucleus accumbens was determined to be correlated with the number of persistent responses made during the decision-making task. It is proposed that top-down control of the orbitofrontal cortex over the ventral striatum is a critical component underlying individual differences in decision making during uncertain conditions.

UR - http://www.scopus.com/inward/record.url?scp=77951298621&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951298621&partnerID=8YFLogxK

U2 - 10.1097/WNR.0b013e3283383482

DO - 10.1097/WNR.0b013e3283383482

M3 - Article

C2 - 20357688

AN - SCOPUS:77951298621

VL - 21

SP - 502

EP - 506

JO - NeuroReport

JF - NeuroReport

SN - 0959-4965

IS - 7

ER -