Hyalinizing trabecular tumor (HTT) is a rare thyroid tumor with low to minimal malignant potential. HTT is often misinterpreted as other thyroid tumors, including papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC), on fine-needle aspiration (FNA) cytology, because of its overlapping cytologic features, such as nuclear grooves and intranulcear pseudoinclusions. Although cytopathologists cannot definitely conclude HTT by FNA cytology, suspicion of HTT is necessary to avoid misdiagnosing HTT as PTC or MTC and to avoid unnecessary aggressive treatment. Here, we report a case of HTT with novel cytologic features in CellPrep liquid based cytology that was diagnosed as suspicious for papillary carcinoma by FNA and finally diagnosed as HTT in the surgical specimen.
Bibliographical noteFunding Information:
This case study was approved by the Institutional Review Board of Seegene Medical Foundation (IRB No. SMF-IRB-2018-001). The need for informed consent was waived.
© 2018 The Korean Society of Pathologists, The Korean Society for Cytopathology.
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine