Hyalinizing trabecular tumor of the thyroid gland, a diagnostic challenge in fine-needle aspiration cytology: Case report

Ye Young Rhee, Hong Kyu Jung, Se Hoon Kim, Soo Hee Kim

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Hyalinizing trabecular tumor (HTT) is a rare thyroid tumor with low to minimal malignant potential. HTT is often misinterpreted as other thyroid tumors, including papillary thyroid carcinoma (PTC) and medullary thyroid carcinoma (MTC), on fine-needle aspiration (FNA) cytology, because of its overlapping cytologic features, such as nuclear grooves and intranulcear pseudoinclusions. Although cytopathologists cannot definitely conclude HTT by FNA cytology, suspicion of HTT is necessary to avoid misdiagnosing HTT as PTC or MTC and to avoid unnecessary aggressive treatment. Here, we report a case of HTT with novel cytologic features in CellPrep liquid based cytology that was diagnosed as suspicious for papillary carcinoma by FNA and finally diagnosed as HTT in the surgical specimen.

Original languageEnglish
Pages (from-to)252-256
Number of pages5
JournalJournal of Pathology and Translational Medicine
Volume52
Issue number4
DOIs
Publication statusPublished - 2018 Jul 1

Bibliographical note

Funding Information:
This case study was approved by the Institutional Review Board of Seegene Medical Foundation (IRB No. SMF-IRB-2018-001). The need for informed consent was waived.

Publisher Copyright:
© 2018 The Korean Society of Pathologists, The Korean Society for Cytopathology.

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

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