Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives

Chul-Ho Jun, Dae Yon Lee, Jun Bae Hong

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Hydroacylation of 1-alkene with a heteroaromatic aldehyde such as pyridinecarboxaldehyde, thiophenecarboxaldehyde and furfural derivatives under cocatalyst of Wilkinson's complex and 2-amino-3-picoline gave poor yield of hydroacylated product. The addition of a catalytic amount of bis(cyclopentadienyl)zirconium dichloride or bis(cyclopentadienyl)titanium dichloride as an additive dramatically increased the yield of the hydroacylated ketone product.

Original languageEnglish
Pages (from-to)6673-6676
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number38
DOIs
Publication statusPublished - 1997 Sep 22

Fingerprint

Picolines
Furaldehyde
Alkenes
Titanium
Ketones
Aldehydes
Derivatives
bis(cyclopentadienyl) zirconium
pyridinecarboxaldehyde
2-amino picoline

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Jun, Chul-Ho ; Lee, Dae Yon ; Hong, Jun Bae. / Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives. In: Tetrahedron Letters. 1997 ; Vol. 38, No. 38. pp. 6673-6676.
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Hydroacylation of 1-alkene with heteroaromatic aldehyde by Rh(I) and additives. / Jun, Chul-Ho; Lee, Dae Yon; Hong, Jun Bae.

In: Tetrahedron Letters, Vol. 38, No. 38, 22.09.1997, p. 6673-6676.

Research output: Contribution to journalArticle

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