Hydrodynamics and magnetophoresis based hybrid blood cell sorter

Hye Kyoung Seo, Hyun Ok Kim, Yong Jun Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The classification of cells is important for medical diagnosis and medicine research. A micro-scale analysis system for blood allows immediate diagnosis, regardless of time or location. Rapid handling of target cells is required for accurate analysis because WBCs are easily altered during cell separation. In previous papers, the reported sample solution flow rates for cell sorting were on the order of tens of micro-liters per minute. This paper proposes a hybrid cell sorter (HCS) that combines hydrodynamics and magnetophoresis. The HCS is proposed for improving the classification efficiency of a virtual impactor-based cell sorter. Also, its performance has been evaluated in the classification of blood cells. The overall classification efficiency of red blood cells (RBCs) increased from 6R26% to 88.63% when using the proposed hybrid scheme. Experimental results show that the classification efficiency of blood cells could be modulated and enhanced by magnetophoresis.

Original languageEnglish
Title of host publication2010 10th IEEE Conference on Nanotechnology, NANO 2010
Pages911-914
Number of pages4
DOIs
Publication statusPublished - 2010 Dec 1
Event2010 10th IEEE Conference on Nanotechnology, NANO 2010 - Ilsan, Gyeonggi-Do, Korea, Republic of
Duration: 2010 Aug 172010 Aug 20

Other

Other2010 10th IEEE Conference on Nanotechnology, NANO 2010
CountryKorea, Republic of
CityIlsan, Gyeonggi-Do
Period10/8/1710/8/20

Fingerprint

blood cells
hydrodynamics
cells
impactors
systems analysis
erythrocytes
classifying
medicine
blood
flow velocity

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

Cite this

Seo, H. K., Kim, H. O., & Kim, Y. J. (2010). Hydrodynamics and magnetophoresis based hybrid blood cell sorter. In 2010 10th IEEE Conference on Nanotechnology, NANO 2010 (pp. 911-914). [5697994] https://doi.org/10.1109/NANO.2010.5697994
Seo, Hye Kyoung ; Kim, Hyun Ok ; Kim, Yong Jun. / Hydrodynamics and magnetophoresis based hybrid blood cell sorter. 2010 10th IEEE Conference on Nanotechnology, NANO 2010. 2010. pp. 911-914
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Seo, HK, Kim, HO & Kim, YJ 2010, Hydrodynamics and magnetophoresis based hybrid blood cell sorter. in 2010 10th IEEE Conference on Nanotechnology, NANO 2010., 5697994, pp. 911-914, 2010 10th IEEE Conference on Nanotechnology, NANO 2010, Ilsan, Gyeonggi-Do, Korea, Republic of, 10/8/17. https://doi.org/10.1109/NANO.2010.5697994

Hydrodynamics and magnetophoresis based hybrid blood cell sorter. / Seo, Hye Kyoung; Kim, Hyun Ok; Kim, Yong Jun.

2010 10th IEEE Conference on Nanotechnology, NANO 2010. 2010. p. 911-914 5697994.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Seo HK, Kim HO, Kim YJ. Hydrodynamics and magnetophoresis based hybrid blood cell sorter. In 2010 10th IEEE Conference on Nanotechnology, NANO 2010. 2010. p. 911-914. 5697994 https://doi.org/10.1109/NANO.2010.5697994