Hypofractionated high-dose intensity-modulated radiotherapy (60 Gy at 2.5 Gy per fraction) for recurrent renal cell carcinoma: A case report

Jaeho Cho, Eon Kim Gwi, Ho Rha Koon, Bae Ahn Joong, Geol Lee Chang, Chang Ok Suh, Jinsil Seong, Chang Keum Ki, Ie Kim Song, Yoon Hee Lee

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A patient with renal cell carcinoma (RCC) developed synchronous bone metastasis with metachronous relapses to the bone and renal fossa. The primary lesion was initially removed surgically, and the metastatic bone lesions and locally recurrent tumours were treated by a high-fractional dose and high-total-dose intensity-modulated radiotherapy (IMRT, 60 Gy at 2.5 Gy per fraction) without significant side effects. All the grossly relapsed tumors underwent complete remission (CR) within a short time after IMRT. To date, CR has been maintained for more than two years. This case study reports the successful treatment of radioresistant RCC using a new scheme that involves a fractionation regimen with a high precision radiotherapy.

Original languageEnglish
Pages (from-to)740-743
Number of pages4
JournalJournal of Korean medical science
Volume23
Issue number4
DOIs
Publication statusPublished - 2008 Aug 1

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Intensity-Modulated Radiotherapy
Renal Cell Carcinoma
Bone and Bones
Neoplasms
Radiotherapy
Neoplasm Metastasis
Kidney
Recurrence
Dose Hypofractionation
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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title = "Hypofractionated high-dose intensity-modulated radiotherapy (60 Gy at 2.5 Gy per fraction) for recurrent renal cell carcinoma: A case report",
abstract = "A patient with renal cell carcinoma (RCC) developed synchronous bone metastasis with metachronous relapses to the bone and renal fossa. The primary lesion was initially removed surgically, and the metastatic bone lesions and locally recurrent tumours were treated by a high-fractional dose and high-total-dose intensity-modulated radiotherapy (IMRT, 60 Gy at 2.5 Gy per fraction) without significant side effects. All the grossly relapsed tumors underwent complete remission (CR) within a short time after IMRT. To date, CR has been maintained for more than two years. This case study reports the successful treatment of radioresistant RCC using a new scheme that involves a fractionation regimen with a high precision radiotherapy.",
author = "Jaeho Cho and Gwi, {Eon Kim} and Koon, {Ho Rha} and Joong, {Bae Ahn} and Chang, {Geol Lee} and Suh, {Chang Ok} and Jinsil Seong and Ki, {Chang Keum} and Song, {Ie Kim} and Lee, {Yoon Hee}",
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Hypofractionated high-dose intensity-modulated radiotherapy (60 Gy at 2.5 Gy per fraction) for recurrent renal cell carcinoma : A case report. / Cho, Jaeho; Gwi, Eon Kim; Koon, Ho Rha; Joong, Bae Ahn; Chang, Geol Lee; Suh, Chang Ok; Seong, Jinsil; Ki, Chang Keum; Song, Ie Kim; Lee, Yoon Hee.

In: Journal of Korean medical science, Vol. 23, No. 4, 01.08.2008, p. 740-743.

Research output: Contribution to journalArticle

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T2 - A case report

AU - Cho, Jaeho

AU - Gwi, Eon Kim

AU - Koon, Ho Rha

AU - Joong, Bae Ahn

AU - Chang, Geol Lee

AU - Suh, Chang Ok

AU - Seong, Jinsil

AU - Ki, Chang Keum

AU - Song, Ie Kim

AU - Lee, Yoon Hee

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AB - A patient with renal cell carcinoma (RCC) developed synchronous bone metastasis with metachronous relapses to the bone and renal fossa. The primary lesion was initially removed surgically, and the metastatic bone lesions and locally recurrent tumours were treated by a high-fractional dose and high-total-dose intensity-modulated radiotherapy (IMRT, 60 Gy at 2.5 Gy per fraction) without significant side effects. All the grossly relapsed tumors underwent complete remission (CR) within a short time after IMRT. To date, CR has been maintained for more than two years. This case study reports the successful treatment of radioresistant RCC using a new scheme that involves a fractionation regimen with a high precision radiotherapy.

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