Hypofractionated high-dose intensity-modulated radiotherapy (60 Gy at 2.5 Gy per fraction) for recurrent renal cell carcinoma: A case report

Jaeho Cho, Eon Kim Gwi, Ho Rha Koon, Bae Ahn Joong, Geol Lee Chang, Chang Ok Suh, Jinsil Seong, Chang Keum Ki, Ie Kim Song, Yoon Hee Lee

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Abstract

A patient with renal cell carcinoma (RCC) developed synchronous bone metastasis with metachronous relapses to the bone and renal fossa. The primary lesion was initially removed surgically, and the metastatic bone lesions and locally recurrent tumours were treated by a high-fractional dose and high-total-dose intensity-modulated radiotherapy (IMRT, 60 Gy at 2.5 Gy per fraction) without significant side effects. All the grossly relapsed tumors underwent complete remission (CR) within a short time after IMRT. To date, CR has been maintained for more than two years. This case study reports the successful treatment of radioresistant RCC using a new scheme that involves a fractionation regimen with a high precision radiotherapy.

Original languageEnglish
Pages (from-to)740-743
Number of pages4
JournalJournal of Korean medical science
Volume23
Issue number4
DOIs
Publication statusPublished - 2008 Aug 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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