IGF-I of serum and vitreous fluid in patients with diabetic proliferative retinopathy

Hyun Chul Lee; Kwan Woo Lee; Choon Hee Chung; Yoon Suk Chung; Eun Jig Lee; Sung Kil Lim; Kyung Rae Kim; Kap Bum Huh; Sung Chul Lee; Oh Woong Kwon

doi:10.1016/0168-8227(94)90024-8

IGF-I of serum and vitreous fluid in patients with diabetic proliferative retinopathy

Hyun Chul Lee, Kwan Woo Lee, Choon Hee Chung, Yoon Suk Chung, Eun Jig Lee, Sung Kil Lim, Kyung Rae Kim, Kap Bum Huh, Sung Chul Lee, Oh Woong Kwon

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Vitreous fluid and serum were obtained at the time of vitrectomy from 15 subjects with diabetic proliferative retinopathy and 6 control subjects. The mean serum IGF-I (IGF-I level: 1 nM/l = 7.7 ng/ml) concentrations were 15.40 ± 4.97 nM/l in controls and 16.24 ± 4.32 nM/l in diabetic patients. The mean vitreous IGF-I concentration was 1.05 ± 0.30 nM/l in controls and 0.91 ± 0.50 nM/l in diabetic patients. There were no significant differences between the two groups, and serum IGF-I concentrations were not correlated with vitreous IGF-I concentrations in the patients with diabetic proliferative retinopathy. These data suggest that IGF-I may not be a risk factor for the development of proliferative diabetic retinpathy.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	Diabetes Research and Clinical Practice
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/0168-8227(94)90024-8
Publication status	Published - 1994 Jun

All Science Journal Classification (ASJC) codes

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/0168-8227(94)90024-8

Cite this

@article{a00c0a0f870e45388b91509bf9aa2ed1,

title = "IGF-I of serum and vitreous fluid in patients with diabetic proliferative retinopathy",

abstract = "Vitreous fluid and serum were obtained at the time of vitrectomy from 15 subjects with diabetic proliferative retinopathy and 6 control subjects. The mean serum IGF-I (IGF-I level: 1 nM/l = 7.7 ng/ml) concentrations were 15.40 ± 4.97 nM/l in controls and 16.24 ± 4.32 nM/l in diabetic patients. The mean vitreous IGF-I concentration was 1.05 ± 0.30 nM/l in controls and 0.91 ± 0.50 nM/l in diabetic patients. There were no significant differences between the two groups, and serum IGF-I concentrations were not correlated with vitreous IGF-I concentrations in the patients with diabetic proliferative retinopathy. These data suggest that IGF-I may not be a risk factor for the development of proliferative diabetic retinpathy.",

author = "Lee, {Hyun Chul} and Lee, {Kwan Woo} and Chung, {Choon Hee} and Chung, {Yoon Suk} and Lee, {Eun Jig} and Lim, {Sung Kil} and Kim, {Kyung Rae} and Huh, {Kap Bum} and Lee, {Sung Chul} and Kwon, {Oh Woong}",

year = "1994",

month = jun,

doi = "10.1016/0168-8227(94)90024-8",

language = "English",

volume = "24",

pages = "85--88",

journal = "Diabetes Research and Clinical Practice",

issn = "0168-8227",

publisher = "Elsevier Ireland Ltd",

number = "2",

}

TY - JOUR

T1 - IGF-I of serum and vitreous fluid in patients with diabetic proliferative retinopathy

AU - Lee, Hyun Chul

AU - Lee, Kwan Woo

AU - Chung, Choon Hee

AU - Chung, Yoon Suk

AU - Lee, Eun Jig

AU - Lim, Sung Kil

AU - Kim, Kyung Rae

AU - Huh, Kap Bum

AU - Lee, Sung Chul

AU - Kwon, Oh Woong

PY - 1994/6

Y1 - 1994/6

N2 - Vitreous fluid and serum were obtained at the time of vitrectomy from 15 subjects with diabetic proliferative retinopathy and 6 control subjects. The mean serum IGF-I (IGF-I level: 1 nM/l = 7.7 ng/ml) concentrations were 15.40 ± 4.97 nM/l in controls and 16.24 ± 4.32 nM/l in diabetic patients. The mean vitreous IGF-I concentration was 1.05 ± 0.30 nM/l in controls and 0.91 ± 0.50 nM/l in diabetic patients. There were no significant differences between the two groups, and serum IGF-I concentrations were not correlated with vitreous IGF-I concentrations in the patients with diabetic proliferative retinopathy. These data suggest that IGF-I may not be a risk factor for the development of proliferative diabetic retinpathy.

AB - Vitreous fluid and serum were obtained at the time of vitrectomy from 15 subjects with diabetic proliferative retinopathy and 6 control subjects. The mean serum IGF-I (IGF-I level: 1 nM/l = 7.7 ng/ml) concentrations were 15.40 ± 4.97 nM/l in controls and 16.24 ± 4.32 nM/l in diabetic patients. The mean vitreous IGF-I concentration was 1.05 ± 0.30 nM/l in controls and 0.91 ± 0.50 nM/l in diabetic patients. There were no significant differences between the two groups, and serum IGF-I concentrations were not correlated with vitreous IGF-I concentrations in the patients with diabetic proliferative retinopathy. These data suggest that IGF-I may not be a risk factor for the development of proliferative diabetic retinpathy.

UR - http://www.scopus.com/inward/record.url?scp=0028093128&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028093128&partnerID=8YFLogxK

U2 - 10.1016/0168-8227(94)90024-8

DO - 10.1016/0168-8227(94)90024-8

M3 - Article

C2 - 7956713

AN - SCOPUS:0028093128

SN - 0168-8227

VL - 24

SP - 85

EP - 88

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

IS - 2

ER -

IGF-I of serum and vitreous fluid in patients with diabetic proliferative retinopathy

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this