Immunoglobulin a nephropathy associated with Plasmodium falciparum malaria

Dong Eun Yoo, Jeong Ho Kim, Jeong Hae Kie, Yoonseon Park, Tae Ik Chang, Hyung Jung Oh, Seung Jun Kim, Tae Hyun Yoo, Kyu Hun Choi, Shin Wook Kang, Seung Hyeok Han

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Abstract

Glomerulonephritis occurs as a rare form of renal manifestation in Plasmodium falciparum malaria. Herein, we report a case of falciparum malaria-associated IgA nephropathy for the first time. A 49-yr old male who had been to East Africa was diagnosed with Plasmodium falciparum malaria. Microhematuria and proteinuria along with acute kidney injury developed during the course of the disease. Kidney biopsy showed mesangial proliferation and IgA deposits with tubulointerstitial inflammation. Laboratory tests after recovery from malaria showed disappearance of urinary abnormalities and normalization of kidney function. Our findings suggest that malaria infection might be associated with IgA nephropathy.

Original languageEnglish
Pages (from-to)446-449
Number of pages4
JournalJournal of Korean medical science
Volume27
Issue number4
DOIs
Publication statusPublished - 2012 Apr 1

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All Science Journal Classification (ASJC) codes

  • Medicine(all)

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