Impact of bifurcation stent technique on clinical outcomes in patients with a Medina 0,0,1 coronary bifurcation lesion: Results from the cobis (coronary bifurcation stenting) II registry

Woo Jin Jang, Young Bin Song, Joo Yong Hahn, Seung Hyuk Choi, Hyo Soo Kim, Cheol Woong Yu, Seung Woon Rha, Yangsoo Jang, Ki Bae Seung, Hyeon Cheol Gwon

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Conclusions: In patients with a Medina 0,0,1 type bifurcation lesion, the 2-stent technique seems to be associated with a better clinical outcome compared with the 1-stent technique. These findings need to be confirmed in randomized controlled trials.

Objective: To compare the long-term clinical outcomes of patients treated with 1-versus 2-stent techniques for Medina 0,0,1 type bifurcation lesions.

Background: Little is known about clinical outcomes and optimal treatment strategies for Medina 0,0,1 type bifurcation lesions.

Methods: A total of 2,897 consecutive patients who underwent percutaneous coronary intervention using a drug-eluting stent for a coronary bifurcation lesion with a side branch (SB) ≥2.3 mm were enrolled from 18 centers in South Korea. We compared target lesion failure (TLF), defined as the composite of cardiac death, myocardial infarction, or target lesion revascularization (TLR) according to 1- or 2-stent techniques in the patients with a de novo Medina 0,0,1 type bifurcation lesion (n = 113, 3.9%).

Results: Fifty patients were treated with the 1-stent technique, and 63 patients with the 2-stent technique. During a median follow-up duration of 36.6 months, patients in the 1-stent technique group tended to have a higher incidence of TLR (3.2 versus 12.0%, P = 0.07) and TLF (4.8 versus 12.0%, P = 0.16) than those in the 2-stent technique group. Multivariate analysis revealed that the 1-stent technique was associated with a higher risk of TLR (hazard ratio [HR] 7.35; 95% confidence interval [CI] 1.27-42.5; P = 0.03) and TLF (HR 4.65; 95% CI1.01-21.6; P = 0.05) than the 2-stent technique.

Original languageEnglish
Pages (from-to)E43-E50
JournalCatheterization and Cardiovascular Interventions
Volume84
Issue number5
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Stents
Registries
Republic of Korea
Drug-Eluting Stents
Percutaneous Coronary Intervention
Multivariate Analysis
Randomized Controlled Trials
Myocardial Infarction
Confidence Intervals
Incidence

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Jang, Woo Jin ; Song, Young Bin ; Hahn, Joo Yong ; Choi, Seung Hyuk ; Kim, Hyo Soo ; Yu, Cheol Woong ; Rha, Seung Woon ; Jang, Yangsoo ; Seung, Ki Bae ; Gwon, Hyeon Cheol. / Impact of bifurcation stent technique on clinical outcomes in patients with a Medina 0,0,1 coronary bifurcation lesion : Results from the cobis (coronary bifurcation stenting) II registry. In: Catheterization and Cardiovascular Interventions. 2014 ; Vol. 84, No. 5. pp. E43-E50.
@article{c0bd63c5efde4d32b9a9bc0298846de5,
title = "Impact of bifurcation stent technique on clinical outcomes in patients with a Medina 0,0,1 coronary bifurcation lesion: Results from the cobis (coronary bifurcation stenting) II registry",
abstract = "Conclusions: In patients with a Medina 0,0,1 type bifurcation lesion, the 2-stent technique seems to be associated with a better clinical outcome compared with the 1-stent technique. These findings need to be confirmed in randomized controlled trials.Objective: To compare the long-term clinical outcomes of patients treated with 1-versus 2-stent techniques for Medina 0,0,1 type bifurcation lesions.Background: Little is known about clinical outcomes and optimal treatment strategies for Medina 0,0,1 type bifurcation lesions.Methods: A total of 2,897 consecutive patients who underwent percutaneous coronary intervention using a drug-eluting stent for a coronary bifurcation lesion with a side branch (SB) ≥2.3 mm were enrolled from 18 centers in South Korea. We compared target lesion failure (TLF), defined as the composite of cardiac death, myocardial infarction, or target lesion revascularization (TLR) according to 1- or 2-stent techniques in the patients with a de novo Medina 0,0,1 type bifurcation lesion (n = 113, 3.9{\%}).Results: Fifty patients were treated with the 1-stent technique, and 63 patients with the 2-stent technique. During a median follow-up duration of 36.6 months, patients in the 1-stent technique group tended to have a higher incidence of TLR (3.2 versus 12.0{\%}, P = 0.07) and TLF (4.8 versus 12.0{\%}, P = 0.16) than those in the 2-stent technique group. Multivariate analysis revealed that the 1-stent technique was associated with a higher risk of TLR (hazard ratio [HR] 7.35; 95{\%} confidence interval [CI] 1.27-42.5; P = 0.03) and TLF (HR 4.65; 95{\%} CI1.01-21.6; P = 0.05) than the 2-stent technique.",
author = "Jang, {Woo Jin} and Song, {Young Bin} and Hahn, {Joo Yong} and Choi, {Seung Hyuk} and Kim, {Hyo Soo} and Yu, {Cheol Woong} and Rha, {Seung Woon} and Yangsoo Jang and Seung, {Ki Bae} and Gwon, {Hyeon Cheol}",
year = "2014",
month = "1",
day = "1",
doi = "10.1002/ccd.25495",
language = "English",
volume = "84",
pages = "E43--E50",
journal = "Catheterization and Cardiovascular Interventions",
issn = "1522-1946",
publisher = "Wiley-Liss Inc.",
number = "5",

}

Impact of bifurcation stent technique on clinical outcomes in patients with a Medina 0,0,1 coronary bifurcation lesion : Results from the cobis (coronary bifurcation stenting) II registry. / Jang, Woo Jin; Song, Young Bin; Hahn, Joo Yong; Choi, Seung Hyuk; Kim, Hyo Soo; Yu, Cheol Woong; Rha, Seung Woon; Jang, Yangsoo; Seung, Ki Bae; Gwon, Hyeon Cheol.

In: Catheterization and Cardiovascular Interventions, Vol. 84, No. 5, 01.01.2014, p. E43-E50.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Impact of bifurcation stent technique on clinical outcomes in patients with a Medina 0,0,1 coronary bifurcation lesion

T2 - Results from the cobis (coronary bifurcation stenting) II registry

AU - Jang, Woo Jin

AU - Song, Young Bin

AU - Hahn, Joo Yong

AU - Choi, Seung Hyuk

AU - Kim, Hyo Soo

AU - Yu, Cheol Woong

AU - Rha, Seung Woon

AU - Jang, Yangsoo

AU - Seung, Ki Bae

AU - Gwon, Hyeon Cheol

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Conclusions: In patients with a Medina 0,0,1 type bifurcation lesion, the 2-stent technique seems to be associated with a better clinical outcome compared with the 1-stent technique. These findings need to be confirmed in randomized controlled trials.Objective: To compare the long-term clinical outcomes of patients treated with 1-versus 2-stent techniques for Medina 0,0,1 type bifurcation lesions.Background: Little is known about clinical outcomes and optimal treatment strategies for Medina 0,0,1 type bifurcation lesions.Methods: A total of 2,897 consecutive patients who underwent percutaneous coronary intervention using a drug-eluting stent for a coronary bifurcation lesion with a side branch (SB) ≥2.3 mm were enrolled from 18 centers in South Korea. We compared target lesion failure (TLF), defined as the composite of cardiac death, myocardial infarction, or target lesion revascularization (TLR) according to 1- or 2-stent techniques in the patients with a de novo Medina 0,0,1 type bifurcation lesion (n = 113, 3.9%).Results: Fifty patients were treated with the 1-stent technique, and 63 patients with the 2-stent technique. During a median follow-up duration of 36.6 months, patients in the 1-stent technique group tended to have a higher incidence of TLR (3.2 versus 12.0%, P = 0.07) and TLF (4.8 versus 12.0%, P = 0.16) than those in the 2-stent technique group. Multivariate analysis revealed that the 1-stent technique was associated with a higher risk of TLR (hazard ratio [HR] 7.35; 95% confidence interval [CI] 1.27-42.5; P = 0.03) and TLF (HR 4.65; 95% CI1.01-21.6; P = 0.05) than the 2-stent technique.

AB - Conclusions: In patients with a Medina 0,0,1 type bifurcation lesion, the 2-stent technique seems to be associated with a better clinical outcome compared with the 1-stent technique. These findings need to be confirmed in randomized controlled trials.Objective: To compare the long-term clinical outcomes of patients treated with 1-versus 2-stent techniques for Medina 0,0,1 type bifurcation lesions.Background: Little is known about clinical outcomes and optimal treatment strategies for Medina 0,0,1 type bifurcation lesions.Methods: A total of 2,897 consecutive patients who underwent percutaneous coronary intervention using a drug-eluting stent for a coronary bifurcation lesion with a side branch (SB) ≥2.3 mm were enrolled from 18 centers in South Korea. We compared target lesion failure (TLF), defined as the composite of cardiac death, myocardial infarction, or target lesion revascularization (TLR) according to 1- or 2-stent techniques in the patients with a de novo Medina 0,0,1 type bifurcation lesion (n = 113, 3.9%).Results: Fifty patients were treated with the 1-stent technique, and 63 patients with the 2-stent technique. During a median follow-up duration of 36.6 months, patients in the 1-stent technique group tended to have a higher incidence of TLR (3.2 versus 12.0%, P = 0.07) and TLF (4.8 versus 12.0%, P = 0.16) than those in the 2-stent technique group. Multivariate analysis revealed that the 1-stent technique was associated with a higher risk of TLR (hazard ratio [HR] 7.35; 95% confidence interval [CI] 1.27-42.5; P = 0.03) and TLF (HR 4.65; 95% CI1.01-21.6; P = 0.05) than the 2-stent technique.

UR - http://www.scopus.com/inward/record.url?scp=84912523952&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84912523952&partnerID=8YFLogxK

U2 - 10.1002/ccd.25495

DO - 10.1002/ccd.25495

M3 - Article

C2 - 24659259

AN - SCOPUS:84912523952

VL - 84

SP - E43-E50

JO - Catheterization and Cardiovascular Interventions

JF - Catheterization and Cardiovascular Interventions

SN - 1522-1946

IS - 5

ER -