Impact of coronary bifurcation angle on clinical outcomes after percutaneous coronary intervention in real-world practice: Results from the COBIS registry

Jeong Hoon Yang, Young Bin Song, Pil Sang Song, Joo Yong Hahn, Seung Hyuk Choi, Jin Ho Choi, Sang Hoon Lee, Hyo Soo Kim, Yangsoo Jang, Seung Jea Tahk, Ki Bae Seung, Seung Jung Park, Hyeon Cheol Gwon

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Objectives: Bifurcation angle has emerged as a predictor of outcome after percutaneous coronary intervention (PCI) for bifurcation lesions. We investigated the impact of bifurcation angle on clinical outcomes in patients undergoing bifurcation lesion PCI. Methods: Consecutive patients who received PCI for bifurcation lesions were enrolled from 16 centers in Korea between January 2004 and June 2006. Patients were divided into low-angle and high-angle groups using the median bifurcation angle (50°). We compared major adverse cardiac events, including cardiac death, myocardial infarction and target lesion revascularization as well as periprocedural outcomes between the 2 groups. Results: We evaluated 1,432 patients with bifurcation lesions with a median follow-up duration of 21 months. The rates of interventional side branch procedures such as guide-wiring of side branches, side-branch ballooning, final kissing ballooning and side-branch stenting were higher in the low-angle group. However, the incidences of major adverse cardiac events and target lesion revascularization were not significantly different between the 2 groups (6.6 vs. 6.9%, p = 0.856 and 4.6 vs. 5.7%, p = 0.375, respectively). Conclusions: Bifurcation angle may not influence long-term clinical outcome in patients with non-left main bifurcation lesion undergoing PCI despite its association with more interventional side-branch procedures.

Original languageEnglish
Pages (from-to)216-224
Number of pages9
JournalCardiology (Switzerland)
Volume122
Issue number4
DOIs
Publication statusPublished - 2012 Sep 1

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Percutaneous Coronary Intervention
Registries
Korea
Myocardial Infarction
Incidence

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

Cite this

Yang, Jeong Hoon ; Song, Young Bin ; Song, Pil Sang ; Hahn, Joo Yong ; Choi, Seung Hyuk ; Choi, Jin Ho ; Lee, Sang Hoon ; Kim, Hyo Soo ; Jang, Yangsoo ; Tahk, Seung Jea ; Seung, Ki Bae ; Park, Seung Jung ; Gwon, Hyeon Cheol. / Impact of coronary bifurcation angle on clinical outcomes after percutaneous coronary intervention in real-world practice : Results from the COBIS registry. In: Cardiology (Switzerland). 2012 ; Vol. 122, No. 4. pp. 216-224.
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title = "Impact of coronary bifurcation angle on clinical outcomes after percutaneous coronary intervention in real-world practice: Results from the COBIS registry",
abstract = "Objectives: Bifurcation angle has emerged as a predictor of outcome after percutaneous coronary intervention (PCI) for bifurcation lesions. We investigated the impact of bifurcation angle on clinical outcomes in patients undergoing bifurcation lesion PCI. Methods: Consecutive patients who received PCI for bifurcation lesions were enrolled from 16 centers in Korea between January 2004 and June 2006. Patients were divided into low-angle and high-angle groups using the median bifurcation angle (50°). We compared major adverse cardiac events, including cardiac death, myocardial infarction and target lesion revascularization as well as periprocedural outcomes between the 2 groups. Results: We evaluated 1,432 patients with bifurcation lesions with a median follow-up duration of 21 months. The rates of interventional side branch procedures such as guide-wiring of side branches, side-branch ballooning, final kissing ballooning and side-branch stenting were higher in the low-angle group. However, the incidences of major adverse cardiac events and target lesion revascularization were not significantly different between the 2 groups (6.6 vs. 6.9{\%}, p = 0.856 and 4.6 vs. 5.7{\%}, p = 0.375, respectively). Conclusions: Bifurcation angle may not influence long-term clinical outcome in patients with non-left main bifurcation lesion undergoing PCI despite its association with more interventional side-branch procedures.",
author = "Yang, {Jeong Hoon} and Song, {Young Bin} and Song, {Pil Sang} and Hahn, {Joo Yong} and Choi, {Seung Hyuk} and Choi, {Jin Ho} and Lee, {Sang Hoon} and Kim, {Hyo Soo} and Yangsoo Jang and Tahk, {Seung Jea} and Seung, {Ki Bae} and Park, {Seung Jung} and Gwon, {Hyeon Cheol}",
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Yang, JH, Song, YB, Song, PS, Hahn, JY, Choi, SH, Choi, JH, Lee, SH, Kim, HS, Jang, Y, Tahk, SJ, Seung, KB, Park, SJ & Gwon, HC 2012, 'Impact of coronary bifurcation angle on clinical outcomes after percutaneous coronary intervention in real-world practice: Results from the COBIS registry', Cardiology (Switzerland), vol. 122, no. 4, pp. 216-224. https://doi.org/10.1159/000338817

Impact of coronary bifurcation angle on clinical outcomes after percutaneous coronary intervention in real-world practice : Results from the COBIS registry. / Yang, Jeong Hoon; Song, Young Bin; Song, Pil Sang; Hahn, Joo Yong; Choi, Seung Hyuk; Choi, Jin Ho; Lee, Sang Hoon; Kim, Hyo Soo; Jang, Yangsoo; Tahk, Seung Jea; Seung, Ki Bae; Park, Seung Jung; Gwon, Hyeon Cheol.

In: Cardiology (Switzerland), Vol. 122, No. 4, 01.09.2012, p. 216-224.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Impact of coronary bifurcation angle on clinical outcomes after percutaneous coronary intervention in real-world practice

T2 - Results from the COBIS registry

AU - Yang, Jeong Hoon

AU - Song, Young Bin

AU - Song, Pil Sang

AU - Hahn, Joo Yong

AU - Choi, Seung Hyuk

AU - Choi, Jin Ho

AU - Lee, Sang Hoon

AU - Kim, Hyo Soo

AU - Jang, Yangsoo

AU - Tahk, Seung Jea

AU - Seung, Ki Bae

AU - Park, Seung Jung

AU - Gwon, Hyeon Cheol

PY - 2012/9/1

Y1 - 2012/9/1

N2 - Objectives: Bifurcation angle has emerged as a predictor of outcome after percutaneous coronary intervention (PCI) for bifurcation lesions. We investigated the impact of bifurcation angle on clinical outcomes in patients undergoing bifurcation lesion PCI. Methods: Consecutive patients who received PCI for bifurcation lesions were enrolled from 16 centers in Korea between January 2004 and June 2006. Patients were divided into low-angle and high-angle groups using the median bifurcation angle (50°). We compared major adverse cardiac events, including cardiac death, myocardial infarction and target lesion revascularization as well as periprocedural outcomes between the 2 groups. Results: We evaluated 1,432 patients with bifurcation lesions with a median follow-up duration of 21 months. The rates of interventional side branch procedures such as guide-wiring of side branches, side-branch ballooning, final kissing ballooning and side-branch stenting were higher in the low-angle group. However, the incidences of major adverse cardiac events and target lesion revascularization were not significantly different between the 2 groups (6.6 vs. 6.9%, p = 0.856 and 4.6 vs. 5.7%, p = 0.375, respectively). Conclusions: Bifurcation angle may not influence long-term clinical outcome in patients with non-left main bifurcation lesion undergoing PCI despite its association with more interventional side-branch procedures.

AB - Objectives: Bifurcation angle has emerged as a predictor of outcome after percutaneous coronary intervention (PCI) for bifurcation lesions. We investigated the impact of bifurcation angle on clinical outcomes in patients undergoing bifurcation lesion PCI. Methods: Consecutive patients who received PCI for bifurcation lesions were enrolled from 16 centers in Korea between January 2004 and June 2006. Patients were divided into low-angle and high-angle groups using the median bifurcation angle (50°). We compared major adverse cardiac events, including cardiac death, myocardial infarction and target lesion revascularization as well as periprocedural outcomes between the 2 groups. Results: We evaluated 1,432 patients with bifurcation lesions with a median follow-up duration of 21 months. The rates of interventional side branch procedures such as guide-wiring of side branches, side-branch ballooning, final kissing ballooning and side-branch stenting were higher in the low-angle group. However, the incidences of major adverse cardiac events and target lesion revascularization were not significantly different between the 2 groups (6.6 vs. 6.9%, p = 0.856 and 4.6 vs. 5.7%, p = 0.375, respectively). Conclusions: Bifurcation angle may not influence long-term clinical outcome in patients with non-left main bifurcation lesion undergoing PCI despite its association with more interventional side-branch procedures.

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