Impact of non-compliant balloons on long-term clinical outcomes in coronary bifurcation lesions: Results from the COBIS (COronary BIfurcation Stent) II registry

Taek Kyu Park, Jae Hwan Lee, Young Bin Song, Jin Ok Jeong, Joo Yong Hahn, Jeong Hoon Yang, Seung Hyuk Choi, Jin Ho Choi, Sang Hoon Lee, Myung Ho Jeong, Hyo Soo Kim, Ju Hyeon Oh, Cheol Woong Yu, Seung Woon Rha, Yangsoo Jang, Jung Han Yoon, Seung Jea Tahk, Ki Bae Seung, Jong Seon Park, Hyeon Cheol Gwon

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Aims: Non-compliant balloons provide uniform radial force along the vessel wall at any inflation pressure. As a result, the use of non-compliant balloons may reduce side branch complications and optimise stent deployment. We sought to investigate the impact of non-compliant balloons on the long-term clinical outcomes of patients undergoing a coronary bifurcation intervention. Methods and results: A total of 2,897 patients treated with drug-eluting stents for bifurcation lesions were enrolled. Non-compliant balloons were used in 752 patients (26%). During a median three-year follow-up, major adverse cardiac events (MACE: cardiac death, myocardial infarction, or target lesion revascularisation) occurred less frequently in the non-compliant balloon group than in the compliant balloon group (8.2% versus 10.9%; p=0.03). After propensity score matching (710 pairs), the use of non-compliant balloons resulted in a lower rate of side branch dissection (0.1% versus 1.1%; p=0.046) and a higher rate of procedural success (79.0% versus 73.9%; p=0.01). The use of non-compliant balloons was associated with a lower risk of MACE (HR 0.64, 95% CI: 0.46-0.91; p=0.01) and cardiac death (HR 0.14, 95% CI: 0.03-0.64; p=0.01). Conclusions: The use of non-compliant balloons was associated with favourable procedural and longterm clinical outcomes in patients receiving coronary bifurcation intervention.

Original languageEnglish
Pages (from-to)456-464
Number of pages9
JournalEuroIntervention
Volume12
Issue number4
DOIs
Publication statusPublished - 2016 Jul

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Park, T. K., Lee, J. H., Song, Y. B., Jeong, J. O., Hahn, J. Y., Yang, J. H., Choi, S. H., Choi, J. H., Lee, S. H., Jeong, M. H., Kim, H. S., Oh, J. H., Yu, C. W., Rha, S. W., Jang, Y., Yoon, J. H., Tahk, S. J., Seung, K. B., Park, J. S., & Gwon, H. C. (2016). Impact of non-compliant balloons on long-term clinical outcomes in coronary bifurcation lesions: Results from the COBIS (COronary BIfurcation Stent) II registry. EuroIntervention, 12(4), 456-464. https://doi.org/10.4244/EIJV12I4A79