Abstract
Purpose: The purposes of this study were (1) to compare health-related quality of life (HRQoL) between Korean childhood cancer survivors and healthy controls and (2) to examine the impact of demographic, diagnosis/treatment, and psychological variables on physical and psychosocial health in survivors.
Methods: The HRQoL (PedsQL), Self-Concept Inventory, and Child Behavior Checklist were administered to childhood cancer survivors, age/gender-matched healthy counterparts, and their parents. Independent-samples t tests and hierarchical multiple regression analyses were conducted.
Results: Compared with healthy controls, childhood cancer survivors reported significantly lower scores across physical and psychosocial HRQoL. For survivors, demographic, diagnosis/treatment, current health status, and psychological variables explained more than 50 % of the variance in both subscales of HRQoL. Especially, self-concept, a psychological variable, explained a significant portion of the variance in physical and psychosocial HRQoL after controlling for cancer-related factors. Several cancer-related factors including time since treatment completion, having a history of allogeneic hematopoietic stem cell transplantation, multiple treatment modalities, and suffering from severe late effects also associated with specific dimension of HRQoL.
Conclusions: Childhood cancer survivors do experience lower level of QoL and psychological factors, especially self-concept, should be considered when supporting the well-being of childhood cancer survivors.
| Original language | English |
|---|---|
| Pages (from-to) | 2603-2612 |
| Number of pages | 10 |
| Journal | Quality of Life Research |
| Volume | 23 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - 2014 Oct 7 |
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All Science Journal Classification (ASJC) codes
- Public Health, Environmental and Occupational Health
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Impact of psychological and cancer-related factors on HRQoL for Korean childhood cancer survivors. / Rhee, Myung Ah; Chung, Kyongmee; Lee, Yuri; Choi, Hana K.; Han, Jung Woo; Kim, Hyo Sun; Kim, Sun Hee; Shin, Yoon Jung; Lyu, Chuhl Joo.
In: Quality of Life Research, Vol. 23, No. 9, 07.10.2014, p. 2603-2612.Research output: Contribution to journal › Article
TY - JOUR
T1 - Impact of psychological and cancer-related factors on HRQoL for Korean childhood cancer survivors
AU - Rhee, Myung Ah
AU - Chung, Kyongmee
AU - Lee, Yuri
AU - Choi, Hana K.
AU - Han, Jung Woo
AU - Kim, Hyo Sun
AU - Kim, Sun Hee
AU - Shin, Yoon Jung
AU - Lyu, Chuhl Joo
PY - 2014/10/7
Y1 - 2014/10/7
N2 - Purpose: The purposes of this study were (1) to compare health-related quality of life (HRQoL) between Korean childhood cancer survivors and healthy controls and (2) to examine the impact of demographic, diagnosis/treatment, and psychological variables on physical and psychosocial health in survivors.Methods: The HRQoL (PedsQL), Self-Concept Inventory, and Child Behavior Checklist were administered to childhood cancer survivors, age/gender-matched healthy counterparts, and their parents. Independent-samples t tests and hierarchical multiple regression analyses were conducted.Results: Compared with healthy controls, childhood cancer survivors reported significantly lower scores across physical and psychosocial HRQoL. For survivors, demographic, diagnosis/treatment, current health status, and psychological variables explained more than 50 % of the variance in both subscales of HRQoL. Especially, self-concept, a psychological variable, explained a significant portion of the variance in physical and psychosocial HRQoL after controlling for cancer-related factors. Several cancer-related factors including time since treatment completion, having a history of allogeneic hematopoietic stem cell transplantation, multiple treatment modalities, and suffering from severe late effects also associated with specific dimension of HRQoL.Conclusions: Childhood cancer survivors do experience lower level of QoL and psychological factors, especially self-concept, should be considered when supporting the well-being of childhood cancer survivors.
AB - Purpose: The purposes of this study were (1) to compare health-related quality of life (HRQoL) between Korean childhood cancer survivors and healthy controls and (2) to examine the impact of demographic, diagnosis/treatment, and psychological variables on physical and psychosocial health in survivors.Methods: The HRQoL (PedsQL), Self-Concept Inventory, and Child Behavior Checklist were administered to childhood cancer survivors, age/gender-matched healthy counterparts, and their parents. Independent-samples t tests and hierarchical multiple regression analyses were conducted.Results: Compared with healthy controls, childhood cancer survivors reported significantly lower scores across physical and psychosocial HRQoL. For survivors, demographic, diagnosis/treatment, current health status, and psychological variables explained more than 50 % of the variance in both subscales of HRQoL. Especially, self-concept, a psychological variable, explained a significant portion of the variance in physical and psychosocial HRQoL after controlling for cancer-related factors. Several cancer-related factors including time since treatment completion, having a history of allogeneic hematopoietic stem cell transplantation, multiple treatment modalities, and suffering from severe late effects also associated with specific dimension of HRQoL.Conclusions: Childhood cancer survivors do experience lower level of QoL and psychological factors, especially self-concept, should be considered when supporting the well-being of childhood cancer survivors.
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U2 - 10.1007/s11136-014-0709-5
DO - 10.1007/s11136-014-0709-5
M3 - Article
VL - 23
SP - 2603
EP - 2612
JO - Quality of Life Research
JF - Quality of Life Research
SN - 0962-9343
IS - 9
ER -