TY - JOUR
T1 - Impact of psychological and cancer-related factors on HRQoL for Korean childhood cancer survivors
AU - Rhee, Myung Ah
AU - Chung, Kyong Mee
AU - Lee, Yuri
AU - Choi, Hana K.
AU - Han, Jung Woo
AU - Kim, Hyo Sun
AU - Kim, Sun Hee
AU - Shin, Yoon Jung
AU - Lyu, Chuhl Joo
N1 - Publisher Copyright:
© 2014, Springer International Publishing Switzerland.
Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2014/10/7
Y1 - 2014/10/7
N2 - Purpose: The purposes of this study were (1) to compare health-related quality of life (HRQoL) between Korean childhood cancer survivors and healthy controls and (2) to examine the impact of demographic, diagnosis/treatment, and psychological variables on physical and psychosocial health in survivors.Methods: The HRQoL (PedsQL), Self-Concept Inventory, and Child Behavior Checklist were administered to childhood cancer survivors, age/gender-matched healthy counterparts, and their parents. Independent-samples t tests and hierarchical multiple regression analyses were conducted.Results: Compared with healthy controls, childhood cancer survivors reported significantly lower scores across physical and psychosocial HRQoL. For survivors, demographic, diagnosis/treatment, current health status, and psychological variables explained more than 50 % of the variance in both subscales of HRQoL. Especially, self-concept, a psychological variable, explained a significant portion of the variance in physical and psychosocial HRQoL after controlling for cancer-related factors. Several cancer-related factors including time since treatment completion, having a history of allogeneic hematopoietic stem cell transplantation, multiple treatment modalities, and suffering from severe late effects also associated with specific dimension of HRQoL.Conclusions: Childhood cancer survivors do experience lower level of QoL and psychological factors, especially self-concept, should be considered when supporting the well-being of childhood cancer survivors.
AB - Purpose: The purposes of this study were (1) to compare health-related quality of life (HRQoL) between Korean childhood cancer survivors and healthy controls and (2) to examine the impact of demographic, diagnosis/treatment, and psychological variables on physical and psychosocial health in survivors.Methods: The HRQoL (PedsQL), Self-Concept Inventory, and Child Behavior Checklist were administered to childhood cancer survivors, age/gender-matched healthy counterparts, and their parents. Independent-samples t tests and hierarchical multiple regression analyses were conducted.Results: Compared with healthy controls, childhood cancer survivors reported significantly lower scores across physical and psychosocial HRQoL. For survivors, demographic, diagnosis/treatment, current health status, and psychological variables explained more than 50 % of the variance in both subscales of HRQoL. Especially, self-concept, a psychological variable, explained a significant portion of the variance in physical and psychosocial HRQoL after controlling for cancer-related factors. Several cancer-related factors including time since treatment completion, having a history of allogeneic hematopoietic stem cell transplantation, multiple treatment modalities, and suffering from severe late effects also associated with specific dimension of HRQoL.Conclusions: Childhood cancer survivors do experience lower level of QoL and psychological factors, especially self-concept, should be considered when supporting the well-being of childhood cancer survivors.
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U2 - 10.1007/s11136-014-0709-5
DO - 10.1007/s11136-014-0709-5
M3 - Article
C2 - 24817318
AN - SCOPUS:84912002946
VL - 23
SP - 2603
EP - 2612
JO - Quality of Life Research
JF - Quality of Life Research
SN - 0962-9343
IS - 9
ER -