Implantable neural probes for chronic electrical recording and optical stimulation

Fan Wu, Eran Stark, Maesoon Im, Il Joo Cho, Lee Tien, Fujun Chen, Eui Sung Yoon, Gyorgi Buzsaki, David Kaplan, Josh Berke, Kensall D. Wise, Euisik Yoon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In order to advance the understanding of brain functions, it is critical to manipulate and monitor the neural circuitry in the cellular level. Supporting optogenetics, silicon probes with monolithically integrated waveguides and electrodes were designed and validated with in-vivo recording of photo-induced neural activity. For chronic applications, we developed a technology that utilizes a biodegradable silk coating to support probes with unique geometries and flexibility for reduced tissue reactions. Consistent recording has been observed for 5 weeks in rats.

Original languageEnglish
Title of host publication2013 IEEE International Electron Devices Meeting, IEDM 2013
Pages8.6.1-8.6.4
DOIs
Publication statusPublished - 2013
Event2013 IEEE International Electron Devices Meeting, IEDM 2013 - Washington, DC, United States
Duration: 2013 Dec 92013 Dec 11

Publication series

NameTechnical Digest - International Electron Devices Meeting, IEDM
ISSN (Print)0163-1918

Other

Other2013 IEEE International Electron Devices Meeting, IEDM 2013
CountryUnited States
CityWashington, DC
Period13/12/913/12/11

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering
  • Materials Chemistry

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