Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands

Gerard A. Crispino, Kyu-Sung Jeong, Hartmuth C. Kolb, Zhi Min Wang, Daqiang Xu, K. Barry Sharpless

Research output: Contribution to journalArticle

231 Citations (Scopus)

Abstract

Bis-cinchona alkaloid substituted pyrimidine ligands were found to give improved enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD) of monosubstituted terminal olefins.
Original languageEnglish
Pages (from-to)3785-3786
Number of pages2
JournalJournal of Organic Chemistry
Volume58
Issue number3785
DOIs
Publication statusPublished - 1993 Jul

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Cinchona Alkaloids
Osmium
Enantioselectivity
Alkenes
Ligands
pyrimidine

Cite this

Crispino, Gerard A. ; Jeong, Kyu-Sung ; Kolb, Hartmuth C. ; Wang, Zhi Min ; Xu, Daqiang ; Sharpless, K. Barry. / Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands. In: Journal of Organic Chemistry. 1993 ; Vol. 58, No. 3785. pp. 3785-3786.
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abstract = "Bis-cinchona alkaloid substituted pyrimidine ligands were found to give improved enantioselectivity in the osmium-catalyzed asymmetric dihydroxylation (AD) of monosubstituted terminal olefins.",
author = "Crispino, {Gerard A.} and Kyu-Sung Jeong and Kolb, {Hartmuth C.} and Wang, {Zhi Min} and Daqiang Xu and Sharpless, {K. Barry}",
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Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands. / Crispino, Gerard A.; Jeong, Kyu-Sung; Kolb, Hartmuth C.; Wang, Zhi Min; Xu, Daqiang; Sharpless, K. Barry.

In: Journal of Organic Chemistry, Vol. 58, No. 3785, 07.1993, p. 3785-3786.

Research output: Contribution to journalArticle

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AU - Crispino, Gerard A.

AU - Jeong, Kyu-Sung

AU - Kolb, Hartmuth C.

AU - Wang, Zhi Min

AU - Xu, Daqiang

AU - Sharpless, K. Barry

PY - 1993/7

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